137219-83-1

Basic information

• Product Name: Phosphinic chloride, bis(3,5-dimethylphenyl)-
• CAS NO: 137219-83-1
• Molecular Formula: C16H18ClOP
• Molecular Weight: 292.745
• Mol File: 137219-83-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phosphinic chloride, bis(3,5-dimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinic chloride, bis(3,5-dimethylphenyl)-(137219-83-1)
• EPA Substance Registry System: Phosphinic chloride, bis(3,5-dimethylphenyl)-(137219-83-1)

Safety Data

• Hazardous Substances Data: 137219-83-1(Hazardous Substances Data)

Upstream product

• 187344-92-9 bis(3,5-dimethylphenyl)phosphine oxide 
• 556-96-7 5-bromo-1,3-xylene 
• 194149-25-2 [bis-(3,5-dimethylphenyl)](diethylamino)phosphine 
• 34696-73-6 3,5-dimethyphenylmagnesium bromide 
• 137219-82-0 Bis(3,5-dimethylphenyl)phosphinic acid 

Downstream Products

• 137219-84-2 2,2'-bis[di-(3,5-dimethylphenyl)phosphoryl]-1,1'-binaphthyl 
• 137219-86-4 2,2'-bis[di(3,5-dimethylphenyl)phosphino]-1,1'-binaphthyl 
• 1198163-29-9 C₂₆H₂₄BrO₂P 
• 1201903-43-6 bis(3,5-dimethylphenyl)phosphinic amide 
• 1201903-44-7 2,2,4,4,6,6-hexa(3,5-dimethylphenyl)cyclotriphosphazene 
• 936475-00-2 (+/-)-pseudo-o-bis(di(3,5-dimethylphenyl)phosphinyl)[2.2]paracyclophane 
• 209981-69-1 5-di(3,5-dimethylphenyl)phosphinyl-1,3-benzodioxole 

Relevant articles and documents

Transition Metal-Free Synthesis of α-Aminophosphine Oxides through C(sp3)?P Coupling of 2-Azaallyls

Radical reactions have been widely applied in C?P bond-forming strategies. Most of these strategies require initiators, transition metal catalysts, or organometallic reagents. Herein, a transition metal-free C(sp3)?P bond formation to prepare α

Kinetic resolution of hydroperoxides with enantiopure phosphines: Preparation of enantioenriched tertiary hydroperoxides

An efficient reductive kinetic resolution strategy capable of accessing optically active tertiary hydroperoxides is reported. Readily accessible tertiary hydroperoxides are resolved with commercially available (R)- or (S)-xylyl-PHANEPHOS with selectivity factors as large as 37. The resulting bis(phosphine oxide) can be recycled in high yields. The isolated mono(phosphine oxide) intermediate resolved hydroperoxides with the same selectivity as the parent bisphosphine. Copyright

Cationic BINAP-Ru(II) Halide Complexes: Highly Efficient Catalysts for Stereoselective Asymmetric Hydrogenation of α- and β-Functionalized Ketones

Cationic ruthenium-BINAP complexes 5, 7, and 10 of the formula Y, where X = Cl, Br, I; Y = Cl, Br, I, BF4, B(C6H5)4; arene = benzene, p-cymene, ethyl benzoate, and their enantiomers have been prepared by the reaction of arene-ruthenium halide complexes 4, 6, and 9 with (S)-BINAP or (R)-BINAP.Structures of the complexes were established by spectroscopy, conductivity, and a single-crystal X-ray analysis (5d: orthorhombic, P21212; a=20.141(2) Angstroem, b=18.504(1) Angstroem, c=12.241(1) Angstroem, V=4562.0(7) Angstroem3, Z=4, R=0.078 for unique 4177 reflections).BINAP derivatives with various substituents at the para and meta positions of four phenyl rings on phosphorus atoms and their cationic Ru(II) complexes have also been synthesized.These BINAP-Ru(II) complexes have been used as catalysts for the asymmetric hydrogenation of various unsaturated organic compounds such as α- and β-keto esters, allylic alcohols, and α,β-unsaturated carboxylic acids in excellent diastereo- and/or enantioselectivities.Catalytic activities and stereoselectivities depend highly on reaction conditions such as solvent, temperature, and additives.Variation of halogen ligands bound to ruthenium atom and substituents on four phenyl rings of BINAP also have exerted remarkable effects on the efficiency of the catalysis.Asymmetric hydrogenation of methyl (+/-)-2-(benzamidomethyl)-3-oxobutanoate catalyzed by the species derived from 9c and 3,5-(t-Bu)2-BINAP afforded the corresponding syn-(2S,3R)-17 in 98percent de and 99percent ee.