138469-95-1

Basic information

• Product Name: 2-Propen-1-one, 3-(dimethylamino)-1-(4-fluoro-2-hydroxyphenyl)-
• Synonyms: 2-Propen-1-one,3-(dimethylamino)-1-(4-fluoro-2-hydroxyphenyl);1-(4-Fluor-2-hydroxyphenyl)-3-dimethylamino-2-propen-1-on;3-dimethylamino-1-(4-fluoro-2-hydroxyphenyl)propenone
• CAS NO: 138469-95-1
• Molecular Formula: C11H12FNO2
• Molecular Weight: 209.22
• Mol File: 138469-95-1.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 325.6±42.0 °C(Predicted)
• Density: 1.202±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Propen-1-one, 3-(dimethylamino)-1-(4-fluoro-2-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-(dimethylamino)-1-(4-fluoro-2-hydroxyphenyl)-(138469-95-1)
• EPA Substance Registry System: 2-Propen-1-one, 3-(dimethylamino)-1-(4-fluoro-2-hydroxyphenyl)-(138469-95-1)

Safety Data

• Hazardous Substances Data: 138469-95-1(Hazardous Substances Data)

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 1481-27-2 4-Fluoro-2-hydroxyacetophenone 

Downstream Products

• 1335285-08-9 (E)-3-(dimethylamino)-1-(4-fluoro-2-(pyridin-2-yloxy)phenyl)prop-2-en-1-one 
• 1335284-93-9 (E)-3-(dimethylamino)-1-(4-fluoro-2-phenoxyphenyl)prop-2-en-1-one 
• 1335284-91-7 (E)-1-(2-(4-chlorophenoxy)-4-fluorophenyl)-3-(dimethylamino)prop-2-en-1-one 
• 1335285-06-7 (E)-3-(dimethylamino)-1-(4-fluoro-2-(o-tolyloxy)phenyl)prop-2-en-1-one 
• 1335284-92-8 (E)-1-(2-(4-bromophenoxy)-4-fluorophenyl)-3-(dimethylamino)prop-2-en-1-one 
• 1335285-05-6 (E)-1-(2-(4-acetylphenoxy)-4-fluorophenyl)-3-(dimethylamino)prop-2-en-1-one 
• 1335285-07-8 (E)-1-(2-(4-fluorophenoxy)-4-fluorophenyl)-3-(dimethylamino)prop-2-en-1-one 
• 1159979-17-5 7-fluoro-4H-chromen-4-one 
• 1159978-73-0 3-bromo-7-fluoro-4H-chromen-4-one 

Relevant articles and documents

Visible-light-driven, radical-triggered tandem cyclization of o-hydroxyaryl enaminones: Facile access to 3-CF2/CF3-containing chromones

A practical and straightforward synthetic route to construct a variety of 3-CF2/CF3-containing chromones via photoredox catalysis was developed. This novel protocol features a visible-light-induced radical-triggered tandem cyclizatio

TBN-triggered, manipulable annulations of: O -hydroxyarylenaminones for divergent syntheses of oximinochromanones and oximinocoumaranones

Divergent synthesis provides an indispensable route to rapid acquisition of structurally diverse chemical scaffolds from identical starting materials. Herein, we describe unprecedented divergent annulations of o-hydroxyarylenaminones promoted by tert-butyl nitrite (TBN) under mild conditions. Two different types of benzo-oxa-heterocycle, including oximinochromanones and oximinocoumaranones, were smoothly assembled with a broad substrate scope and good functional group compatibility.

Convenient and Rapid Synthesis of 3-Selenocyanato-4 H -chromen-4-ones

A sequential one-pot, simple and convenient method is described for the synthesis of 3-selenocyanato-4 H -chromen-4-ones by addition, first of DMF-DMA and then of triselenodicyanide as electrophile.