1394075-79-6

Basic information

• Product Name: 1-cyclopropyl-3-(4-(6-oxo-5-(tetrahydro-2H-pyran-4-yl)-5,6,6a,7,9,10-hexahydro-[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
• Synonyms: 1-cyclopropyl-3-(4-(6-oxo-5-(tetrahydro-2H-pyran-4-yl)-5,6,6a,7,9,10-hexahydro-[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
• CAS NO: 1394075-79-6
• Molecular Weight: 464.524
• Mol File: 1394075-79-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-cyclopropyl-3-(4-(6-oxo-5-(tetrahydro-2H-pyran-4-yl)-5,6,6a,7,9,10-hexahydro-[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclopropyl-3-(4-(6-oxo-5-(tetrahydro-2H-pyran-4-yl)-5,6,6a,7,9,10-hexahydro-[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea(1394075-79-6)
• EPA Substance Registry System: 1-cyclopropyl-3-(4-(6-oxo-5-(tetrahydro-2H-pyran-4-yl)-5,6,6a,7,9,10-hexahydro-[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea(1394075-79-6)

Safety Data

• Hazardous Substances Data: 1394075-79-6(Hazardous Substances Data)

Upstream product

• 1394070-78-0 4-(5-bromo-2-chloropyrimidin-4-yl)morpholine-3-carboxylic acid 
• 1394071-07-8 4-(5-bromo-2-chloropyrimidin-4-yl)-N-(tetrahydro-2H-pyran-4-yl)morpholine-3-carboxamide 
• 874297-79-7 1-cyclopropyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea 
• 1268474-95-8 2-chloro-5-(tetrahydro-2H-pyran-4-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one 

Relevant articles and documents

N-SUBSTITUTED OXAZINOPTERIDINES AND OXAZINOPTERIDINONES

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein Ar, R1, R2, R3, G1, G2, and m are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating inflammatory disorders, cardiovascular disease, cancer, and other conditions associated with PI3Kδ.