874297-79-7

Basic information

• Product Name: 1-CYCLOPROPYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA
• Synonyms: 1-CYCLOPROPYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA;4-(3-CYCLOPROPYLUREIDO)PHENYLBORONIC ACID, PINACOL ESTER;4-(3-Cyclopropylureido)benzeneboronic acid, pinacol ester;4-[(Cyclopropylcarbamoyl)amino]benzeneboronic acid, pinacol ester;4-[(Cyclopropylcarbamoyl)amino]benzeneboronic acid, pinacol ester 97%;4-(3-Cyclopropylureido)phenylboronic acid,pinacol;Urea, N-cyclopropyl-N'-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]-;4-[(Cyclopropylcarbamoyl)amino]benzeneboronicacid,pinacolester97%
• CAS NO: 874297-79-7
• Molecular Formula: C₁₆H₂₃BN₂O₃
• Molecular Weight: 302.18
• Product Categories: blocks;BoronicAcids
• Mol File: 874297-79-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 227-229
• Boiling Point: 414.8 °C at 760 mmHg
• Flash Point: 204.7 °C
• Appearance: /
• Density: 1.14 g/cm³
• Vapor Pressure: 4.31E-07mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: Keep Cold
• PKA: 13.79±0.20(Predicted)
• CAS DataBase Reference: 1-CYCLOPROPYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CYCLOPROPYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA(874297-79-7)
• EPA Substance Registry System: 1-CYCLOPROPYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA(874297-79-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 874297-79-7(Hazardous Substances Data)

Usage

General Description

1-CYCLOPROPYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA is a chemical compound that contains a urea group and a boron-containing dioxaborolane ring. It is a cyclopropyl derivative of phenylurea, and its structure includes a tetramethyl-substituted dioxaborolane moiety. This chemical is a potential candidate for use in pharmaceuticals or agrochemicals due to the presence of both the urea and boron groups, which have diverse applications in drug development and crop protection. Its unique structure and properties make it of interest for further study and potential use in various industries.

InChI:InChI=1/C16H23BN2O3/c1-15(2)16(3,4)22-17(21-15)11-5-7-12(8-6-11)18-14(20)19-13-9-10-13/h5-8,13H,9-10H2,1-4H3,(H2,18,19,20)

Upstream product

• 765-30-0 Cyclopropylamine 

Downstream Products

• 1250868-52-0 1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-((dimethylamino)methyl)pyrimidin-2-yl)phenyl)-3-cyclopropylurea monotrifluoroacetate 
• 1429638-98-1 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-2-yl)phenyl)urea 
• 1429638-97-0 1-cyclopropyl-3-(4-(7-methyl-4-((S)-3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)urea 
• 1429638-96-9 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-5,5-dioxido-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)phenyl)urea 
• 1429638-95-8 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-6,6-dioxido-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-yl)phenyl)urea 
• 1429638-94-7 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-yl)phenyl)urea 
• 1429638-93-6 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)urea 
• 1429638-92-5 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)urea 
• 1402551-52-3 tert-butyl 2-chloro-4-(4-(3-cyclopropylureido)phenyl)-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate 
• 1402551-62-5 tert-butyl 4-(4-((S)-3-methylmorpholine-4-carboxamido)phenyl)-2-((S)-3-methylmorpholino)-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate 
• 1402551-55-6 (S)-tert-butyl 4-(4-((ethoxycarbonyl)amino)phenyl)-2-(3-methylmorpholino)-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate 
• 1394075-79-6 1-cyclopropyl-3-(4-(6-oxo-5-(tetrahydro-2H-pyran-4-yl)-5,6,6a,7,9,10-hexahydro-[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea 
• 1333108-18-1 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-6-(pyridin-3-yl)pyrimidin-2-yl)phenyl)urea 
• 1333108-41-0 1-cyclopropyl-3-(4-(2-morpholinopyrimidin-4-yl)phenyl)urea 

Relevant articles and documents

PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES

The invention relates to pyrimidine compounds of the Formula I: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.