140134-21-0

Basic information

• Product Name: (R,R)-N-BENZYL-3,4-TRANS-DIAMINOPYRROLIDINE
• Synonyms: (R,R)-N-BENZYL-3,4-TRANS-DIAMINOPYRROLIDINE;(3R,4R)-1-BENZYLPYRROLIDINE-3,4-DIAMINE;(3R,4R)-(-)-3,4-DiaMino-1-benzylpyrrolidine;(3R,4R)-(-)-1-Benzyl-3,4-pyrrolidinediamine
• CAS NO: 140134-21-0
• Molecular Formula: C₁₁H₁₇N₃
• Molecular Weight: 191.27
• Mol File: 140134-21-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 296.8±40.0 °C(Predicted)
• Appearance: /
• Density: 1.104±0.06 g/cm3(Predicted)
• PKA: 9.65±0.40(Predicted)
• CAS DataBase Reference: (R,R)-N-BENZYL-3,4-TRANS-DIAMINOPYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R,R)-N-BENZYL-3,4-TRANS-DIAMINOPYRROLIDINE(140134-21-0)
• EPA Substance Registry System: (R,R)-N-BENZYL-3,4-TRANS-DIAMINOPYRROLIDINE(140134-21-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• Hazardous Substances Data: 140134-21-0(Hazardous Substances Data)

Usage

General Description

(R,R)-N-Benzyl-3,4-trans-diaminopyrrolidine is a chemical compound that is classified as a diaminopyrrolidine. It consists of a benzyl group attached to a pyrrolidine ring, with two amino groups located on different carbon atoms in a trans configuration. (R,R)-N-BENZYL-3,4-TRANS-DIAMINOPYRROLIDINE is a versatile building block in organic synthesis and can be used in the development of pharmaceuticals and other fine chemical products. Its unique structure allows for the synthesis of complex molecules and has potential applications in the creation of chiral catalysts and ligands. Additionally, its use in the development of new materials and drugs makes it an important compound in the field of organic chemistry.

Upstream product

• 140134-20-9 (3R,4R)-3,4-diazido-1-benzylpyrrolidine 
• 104351-40-8 (3S,4S)-1-benzyl-3,4-pyrrolidinediyl bis(methanesulfonate) 
• 100-46-9 benzylamine 
• 75172-31-5 (3R,4R)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione 
• 90365-74-5 (3S,4S)-(+)-1-benzyl-3,4-pyrrolidinediol 
• 136137-85-4 (3R,4R)-1-benzyl-2,5-dioxopyrrolidine-3,4-diyl diacetate 

Downstream Products

• 140134-22-1 C₂₅H₂₅N₃O₂ 
• 205251-35-0 N-benzyl-3,4-di(Boc-amino)pyrrolidine 
• 917897-66-6 (3R,4R)-1-benzyl-3,4-bis(trifluoromethylsulfonamido)pyrrolidine 
• 205251-36-1 [(3R,4R)-1-Benzyl-4-(tert-butoxycarbonyl-methyl-amino)-pyrrolidin-3-yl]-methyl-carbamic acid tert-butyl ester 
• 1052274-38-0 C₃₁H₄₅N₃O₆S₂ 
• 1228314-72-4 (3R,4R)-N',N''-bis[3'-t-butylsalicylidene]-N-benzyl-3,4-diaminopyrrolidine 
• 1228314-76-8 C₂₇H₂₉N₃O₂ 
• 140134-22-1 C₂₅H₂₅N₃O₂ 
• 1021949-23-4 C₂₇H₂₉N₃O₄ 
• 1021949-26-7 C₃₃H₂₉N₃O₂ 
• 1021949-25-6 (3R,4R)-N₃,N₄-bis[3,5-di-t-butylsalicylidene]-1-benzyl-3,4-diaminopyrrolidine 
• 1228314-74-6 C₃₃H₂₉N₃O₂ 
• 1449329-07-0 C₃₃H₅₃N₇O₈ 

Relevant articles and documents

The synthesis of tetradentate salens derived from (3R,4R)-N-substituted-3, 4-diaminopyrrolidines and their application in the enantioselective trimethylsilylcyanation of aromatic aldehydes

The in situ formed Ti(IV) complexes of pyrrolidine-based chiral salen ligands derived from natural l-tartaric acid were evaluated as catalysts in the enantioselective trimethylsilylcyanation of aromatic aldehydes. The different activity and selectivity of the catalysts in the formation of the products were found to be dependent on the N-substituent of the pyrrolidine.

Synthesis of an ovoid chiral cage

Evidence for the formation of an ovoid chiral cage, resulting from the auto-assembly of two hexafunctional and three tetrafunctional modules reacting through dynamic covalent bond formation, is provided. Georg Thieme Verlag Stuttgart.

Design of a C2-symmetric chiral pyrrolidine-based amino sulfonamide: application to anti-selective direct asymmetric Mannich reactions

The anti-selective direct asymmetric Mannich reaction was found to be efficiently catalyzed by the novel pyrrolidine-based amino sulfonamide (R,R)-2 prepared from l-tartaric acid.