1407499-61-9

Basic information

• Product Name: N'-(3-(1H-indol-3-yl)propanoyl)-N'-isopropylbenzohydrazide
• Synonyms: N'-(3-(1H-indol-3-yl)propanoyl)-N'-isopropylbenzohydrazide
• CAS NO: 1407499-61-9
• Molecular Weight: 349.433
• Mol File: 1407499-61-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N'-(3-(1H-indol-3-yl)propanoyl)-N'-isopropylbenzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(3-(1H-indol-3-yl)propanoyl)-N'-isopropylbenzohydrazide(1407499-61-9)
• EPA Substance Registry System: N'-(3-(1H-indol-3-yl)propanoyl)-N'-isopropylbenzohydrazide(1407499-61-9)

Safety Data

• Hazardous Substances Data: 1407499-61-9(Hazardous Substances Data)

Upstream product

• 3408-16-0 benzoic acid isopropylidenehydrazide 
• 613-94-5 benzoic acid hydrazide 
• 830-96-6 Indole-3-propionic acid 
• 3408-21-7 1-benzoyl-2-isopropylhydrazine 

Downstream Products

• 1407499-62-0 tert-butyl 3-(3-(2-benzoyl-1-isopropylhydrazinyl)-3-oxopropyl)-1H-indole-1-carboxylate 
• 1407499-59-5 N'-(3-(1-benzyl-1H-indol-3-yl)propanoyl)-N'-isopropylbenzohydrazide 

Relevant articles and documents

Discovery of a novel series of indolyl hydrazide derivatives as diacylglycerol acyltransferase-1 inhibitors

A novel series of hydrazide derivatives were synthesized as potential diacylglycerol acyltransferase (DGAT) inhibitors. Among them, compounds 8u and 8v exhibited selective and potent DGAT-1 inhibitory activities. In addition, compound 8u dose-dependently inhibited triglyceride synthesis in HepG2 cell lines. Furthermore, treatment with compound 8u for an oral lipid tolerance test showed a significant decrease in plasma triglyceride levels compared with vehicle-treated control animals, indicating delayed absorption of triglyceride after an acute lipid challenge.