141336-67-6

Basic information

• Product Name: Cycloheptanecarbonitrile, 1-(phenylmethyl)-
• CAS NO: 141336-67-6
• Molecular Formula: C15H19N
• Molecular Weight: 213.323
• Mol File: 141336-67-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cycloheptanecarbonitrile, 1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cycloheptanecarbonitrile, 1-(phenylmethyl)-(141336-67-6)
• EPA Substance Registry System: Cycloheptanecarbonitrile, 1-(phenylmethyl)-(141336-67-6)

Safety Data

• Hazardous Substances Data: 141336-67-6(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 629-03-8 1 ,6-dibromohexane 
• 32730-85-1 cycloheptanecarbonitrile 
• 100-44-7 benzyl chloride 

Relevant articles and documents

Sulfone–Metal Exchange and Alkylation of Sulfonylnitriles

The first general sulfone–metal exchange is described. Treating substituted 2-pyridylsulfonylacetonitriles with either BuLi or Bu3MgLi generates metalated nitriles that efficiently intercept a variety of electrophiles to afford quaternary nitriles. The 2-pyridylsulfone is critical for the sulfone–metal exchange because chelation anchors the organometallic proximal to the electrophilic, tetrasubstituted sulfone to override complex-induced deprotonation. Alkylating commercial 2-pyridinesulfonylacetonitrile with mild bases, either K2CO3 or DBU, and subsequent sulfone–metal exchange and alkylation rapidly assembles quaternary nitriles by three alkylations, only one of which requires an organometallic reagent.

Substituted sulfonamides, process of preparation and medicines containing same

The present invention concerns new substituted sulfonamides, and the physiologically acceptable salts possibly in the form of complexes, esters and amides thereof, represented by the formula: STR1