629-03-8 Usage
Description
1,6-Dibromohexane is a colorless or pale yellow liquid that is soluble in ethanol, ether, benzene, and chloroform, but insoluble in water. It is a chemical compound with the molecular formula C6H12Br2 and is known for its various applications in the synthesis of different compounds and materials.
Uses
1. Used in Pharmaceutical Synthesis:
1,6-Dibromohexane is used as a reagent in the synthesis of novel benzo[b]xanthone derivatives, which have potential antitumor activity. This application highlights its importance in the development of new cancer treatments.
2. Used in Cross-linking of Glycuronans:
1,6-Dibromohexane serves as a cross-linker for the cross-linking of glycuronans, which are essential components of various biological structures, such as the extracellular matrix and cell surfaces.
3. Used in Polymer Synthesis for Alkaline Fuel Cell Applications:
1,6-Dibromohexane is used to introduce a C6 spacer in the molecular architecture of solvent processable and conductive polyfluorene ionomers, which are crucial for alkaline fuel cell applications.
4. Used in Polymer Photovoltaic Cells:
It is utilized in the synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) to stabilize the film morphology in polymer photovoltaic cells, enhancing their performance and efficiency.
5. Used in Redox Switching Behavior Studies:
1,6-Dibromohexane is employed in the synthesis of pyrrolo-tetrathiafulvalene molecular bridge (6PTTF6) to study the redox switching behavior of single molecules, which is vital for understanding and developing molecular-scale electronic devices.
6. Used in Water-soluble Thermoresponsive Polylactides:
It is used in the synthesis of water-soluble thermoresponsive polylactides, which have potential applications in the biomedical and pharmaceutical industries, such as drug delivery systems and temperature-sensitive materials.
7. Used in the Synthesis of Hexamethonium Bromide:
1,6-Dibromohexane is also used in the synthesis of the hypotensive drug hexamethonium bromide, which is an important medication for treating high blood pressure.
Preparation
1,6-Dibromohexane is synthesized from hexanediol by bromination.
Check Digit Verification of cas no
The CAS Registry Mumber 629-03-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 629-03:
(5*6)+(4*2)+(3*9)+(2*0)+(1*3)=68
68 % 10 = 8
So 629-03-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H12Br2/c7-5-3-1-2-4-6-8/h1-6H2
629-03-8Relevant articles and documents
Stable and easily available sulfide surrogates allow a stereoselective activation of alcohols
Brutiu, Bogdan R.,Drescher, Martina,Matya?ovsky, Ján,Maulide, Nuno,Merad, Jérémy,Pinto, Alexandre,Stopka, Tobias
, p. 7770 - 7774 (2021/06/16)
Isothiouronium salts are easily accessible and stable compounds. Herein, we report their use as versatile deoxasulfenylating agents enabling a stereoselective, thiol-free protocol for synthesis of thioethers from alcohols. The method is simple, scalable and tolerates a broad range of functional groups otherwise incompatible with other methods. Late-stage modification of several pharmaceuticals provides access to multiple analogues of biologically relevant molecules. Performed experiments give insight into the reaction mechanism.
Biomolecule interaction using atomic force microscope
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Page/Page column, (2014/03/26)
The present patent application describes a cantilever for atomic force microscopy (AFM), which includes a cantilever body having a fixed end and a free end, the free end having a surface region being chemically modified by a dendron in which a plurality of termini of the branched region of the dendron are bound to the surface, and a terminus of the linear region of the dendron is functionalized.
Method for preparing n-(γ(v)-bromoalkyl)phthalimides
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Page 3-4, (2008/06/13)
The invention concerns a procedure for preparation of N-(ω-bromoalkyl)phthalimides which consists of reacting potassium phthalimide with an α,ω-dibromoalkane without cosolvent, at a temperature from 50° C. to 130° C. by using a molar ratio of α,ω-dibromoalkane to potassium phthalimide from 2.5 to 6, then of removing excess α,ω-dibromoalkane, under reduced pressure at a temperature equal to 150° C. at most, of taking up the reaction medium again with a low boiling point alcohol at a temperature near that of the boiling point of said alcohol, of filtering at this temperature, of cooling the filtrate obtained and then of recovering the N-(ω-bromoalkyl)phthalimide.