235095-05-3

Basic information

• Product Name: 1-azido-6-broMo-Hexane
• Synonyms: 1-azido-6-broMo-Hexane
• CAS NO: 235095-05-3
• Molecular Formula: C₆H₁₂BrN₃
• Molecular Weight: 206.08358
• Mol File: 235095-05-3.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-azido-6-broMo-Hexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-azido-6-broMo-Hexane(235095-05-3)
• EPA Substance Registry System: 1-azido-6-broMo-Hexane(235095-05-3)

Safety Data

• Hazardous Substances Data: 235095-05-3(Hazardous Substances Data)

Usage

General Description

1-Azido-6-bromo-hexane is a chemical compound with the molecular formula C6H12BrN3. It is in the chemical class of organic compounds known as mononitro compounds, which contain a nitro group attached to a carbon atom. This reactive compound incorporates both an azido group, which is a functional group consisting of two nitrogen atoms linked to a third, more electroneutrally bound nitrogen, and a bromo group, making it versatile for various chemical reactions. Across scientific research, it is employed as a starting material or intermediate in the synthesis of other complex molecules. The specifics regarding its synthesis, physical characteristics, and potential hazards are dependent on experimental conditions.

Upstream product

• 629-03-8 1 ,6-dibromohexane 
• 4286-55-9 1-bromo-6-hexanol 
• 146292-90-2 6-azidohexan-1-ol 
• 2695-47-8 6-Bromo-1-hexene 

Downstream Products

• 400614-31-5 2,3,6-tri-O-benzyl-α-D-galactopyranosyl-(1->1)-2,3,4-tri-O-benzyl-6-O-(6-azidohexyl)-α-D-glucopyranoside 
• 500567-74-8 5-(6-azido-hexyloxy)-benzene-1,3-dicarbaldehyde 
• 945259-80-3 C₃₆H₇₃N₃O₆ 
• 945259-81-4 C₄₂H₈₄N₆O₆ 
• 400614-21-3 α-D-galactopyranosyl-(1->1)-6-O-(6-acrylamidohexyl)-α-D-glucopyranoside 
• 1124219-19-7 4-C-[methyl (5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosyl)onate]-N-(6-azidohexyl)-4-piperidinol 
• 1161826-30-7 6-azidohexyl 3β-hydroxyolean-12-en-28-oate 
• 1144106-76-2 7-(4-(2-(2-azidoethoxy)ethyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1246635-34-6 N-(6-azidohexyl)-2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol 
• 1338728-76-9 4-(6-azidohexyl)-1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene borane 
• 1338728-75-8 4-(6-azidohexyl)-1,3-diisopropylimidazol-2-ylidene borane 
• 1338728-96-3 4-(6-azidohexyl)-1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene iodoborane 
• 1338728-98-5 4-(6-aminohexyl)-1,3-bis(2,6-diisopropylphenyl)imidazolium iodide 
• 1338729-00-2 4-(6-(4-(4-bromophenyl)-1,2,3-triazol-1-yl)hexyl)-1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene borane 

Relevant articles and documents

Epoxides related to dioncoquinone B: Synthesis, activity against multiple myeloma cells, and search for the target protein

Epoxide 2b is an analog of the synthetic intermediate 2a en route to the polyketide-derived antitumoral naphthoquinone dioncoquinone B (1), isolated from cell cultures of the tropical liana Triphyophyllum peltatum (Dioncophyllaceae). Compound 2b was found to induce strong apoptosis in multiple myeloma cells at a concentration (EC50 = 3.5 μM), distinctly lower than that of 1 and any related analog, without exerting significant toxicity against normal blood cells. Preliminary studies showed that 2b follows different SAR rules as compared to the naphthoquinones. Among the series of synthesized epoxides, 2b was the most active one and was thus, after biotinylation, subjected to mass spectrometry-based affinity capture experiments aiming at the identification of target proteins. The MS data revealed 2b to address proteins that are associated with stress regulation processes which are critical for multiple myeloma cell survival.

Synthesis and photophysical studies on triazole bridged dendrimers with phenothiazine as surface unit

Synthesis and photophysical properties of some novel 1, 2, 3-triazole bridged phenothiazine dendrimers with enone and S-(-)-BINOL core is described. ARKAT-USA, Inc.

ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS

The present invention provides processes for the synthesis of organic azides, intermediates for the production thereof, and compositions related thereto.

Direct Intermolecular Anti-Markovnikov Hydroazidation of Unactivated Olefins

We herein report a direct intermolecular anti-Markovnikov hydroazidation method for unactivated olefins, which is promoted by a catalytic amount of bench-stable benziodoxole at ambient temperature. This method facilitates previously difficult, direct addition of hydrazoic acid across a wide variety of unactivated olefins in both complex molecules and unfunctionalized commodity chemicals. It conveniently fills a synthetic chemistry gap of existing olefin hydroazidation procedures, and thereby provides a valuable tool for azido-group labeling in organic synthesis and chemical biology studies.