144155-24-8 Usage
Properties
1. Chemical compound
2. Molecular formula: C21H12Cl3NO2
3. Acridine derivative
4. Contains two chlorine atoms and a phenyl group
5. Used in the synthesis of pharmaceuticals and agrochemicals
6. Used as a research chemical in organic chemistry and medicinal chemistry
7. Versatile building block for the development of new drugs and biologically active compounds
8. Potential for fluorescence and DNA binding properties
9. Useful tool in biochemical and molecular biology research
10. May pose health and environmental risks
Content
1. Chemical compound: 6-Chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione
2. Molecular formula: C21H12Cl3NO2
3. Structure: Contains two chlorine atoms and a phenyl group
4. Uses: Synthesis of pharmaceuticals and agrochemicals
5. Applications: Research chemical in organic chemistry and medicinal chemistry
6. Versatility: Building block for new drugs and biologically active compounds
7. Properties: Potential for fluorescence and DNA binding
8. Research tool: Useful in biochemical and molecular biology research
9. Safety: Handle with care due to potential health and environmental risks.
Check Digit Verification of cas no
The CAS Registry Mumber 144155-24-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,1,5 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 144155-24:
(8*1)+(7*4)+(6*4)+(5*1)+(4*5)+(3*5)+(2*2)+(1*4)=108
108 % 10 = 8
So 144155-24-8 is a valid CAS Registry Number.
144155-24-8Relevant articles and documents
Synthesis and Antimalarial Properties of 1-Imino Derivatives of 7-Chloro-3-substituted-3,4-dihydro-1,9(2H,10H)-acridinediones and Related Structures
Kesten, Stephen J.,Degnan, Margaret J.,Hung, Jocelyn,McNamara, Dennis J.,Ortwine, Daniel F.,et al.
, p. 3429 - 3447 (2007/10/02)
To improve upon the activity and properties of the 3-aryl-7-chloro-3,4-dihydro-1,9(2H,10H)-acridinediones, a variety of 1-imino derivatives (3) were prepared and shown to be highly active antimalarial agents in both rodents and primates.Among structural modifications prepared, including N10-alkyl and C2-substituted analogs, removal of the C9 oxygen, and introduction of an imino side chain at C9, the imines of the N10-H acridinediones were the most active compounds obtained.The imino derivative of7-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione (9aa) proved to be highly active in advanced studies in primates.