40928-13-0

Basic information

• Product Name: 4-Chloro-isatoic anhydride
• Synonyms: AURORA KA-6696;4-CHLORO-ISATOIC ANHYDRIDE;7-CHLOROISATOIC ANHYDRIDE;7-CHLORO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE;6-CHLOROISATOIC ANHYDRIDE;4-CHLOROISATONIC ANHYDRIDE;7-Chloro-2H-3,1-benzoxazine-2,4(1H)-dione, 7-Chloroisatoic anhydride;7-chloro-2H-3,1-benzoxazine-2,4(1H)-dione
• CAS NO: 40928-13-0
• Molecular Formula: C₈H₄ClNO₃
• Molecular Weight: 197.58
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Heterocyclic Compounds;Benzoxazines;Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks
• Mol File: 40928-13-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 255-259 °C
• Appearance: /
• Density: 1.54 g/cm³
• Refractive Index: 1.6
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: soluble in Dimethylformamide
• PKA: 9.95±0.20(Predicted)
• CAS DataBase Reference: 4-Chloro-isatoic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-isatoic anhydride(40928-13-0)
• EPA Substance Registry System: 4-Chloro-isatoic anhydride(40928-13-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 40928-13-0(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 613, 1961 DOI: 10.1021/jo01061a618

InChI:InChI=1/C8H4ClNO3/c9-4-1-2-5-6(3-4)10-8(12)13-7(5)11/h1-3H,(H,10,12)

Upstream product

• 75-44-5 phosgene 
• 497-19-8 sodium carbonate 
• 89-77-0 2-Amino-4-chlorobenzoic acid 

Downstream Products

• 37795-81-6 6-chloro-2,3-dihydro-isoxazolo[3,2-b]quinazolin-9-one 
• 20887-04-1 2-amino-4-chloro-N-phenylbenzamide 
• 87296-89-7 2-Amino-4-chloro-N-(4-methyl-piperazin-1-yl)-benzamide 
• 144155-24-8 6-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione 
• 144155-27-1 6-Chloro-3-(4-trifluoromethyl-phenyl)-3,4-dihydro-2H,10H-acridine-1,9-dione 
• 110552-67-5 2-Amino-4-chloro-N-(3-imidazol-1-yl-2-methyl-propyl)-benzamide 
• 110552-66-4 2-Amino-4-chloro-N-(5-imidazol-1-yl-pentyl)-benzamide 
• 75787-31-4 amino-2 chloro-4 N₂,N₂ dimethylbenzohydrazide 
• 110552-65-3 2-Amino-4-chloro-N-(4-imidazol-1-yl-butyl)-benzamide 
• 195983-60-9 8-chloro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione 
• 35709-36-5 4-chloro-N-benzylisatoic anhydride 
• 705977-14-6 2-amino-N-(benzyloxy)-4-chlorobenzamide 
• 214971-18-3 4-chloroanthranilic acid N-methoxy-N-methylamide 
• 791098-01-6 1-(2-amino-4-chlorobenzoyl)piperidine 

Relevant articles and documents

Quinazolinone inhibitors of cGMP phosphodiesterase

Novel quinazolinone compounds, methods of using such compounds in the treatment of cGMP-associated conditions such as erectile dysfunction, and pharmaceutical compositions containing such compounds.