144461-19-8 Usage
General Description
1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(R)-, also known as R-(?)-2-(2,2-Diethoxyethyloxy)-1,3-propanediol monoacetate, is a chemical compound used in the production of pharmaceuticals, cosmetics, and personal care products. It is a clear, colorless liquid with a molecular formula of C10H20O5 and a molecular weight of 220.25 g/mol. 1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(R)- is often used as a chiral building block in organic synthesis due to its ability to participate in a variety of chemical reactions. It is also considered to be a safe and environmentally friendly alternative to other chemicals commonly used in similar applications. Furthermore, this compound is commonly found in industrial and laboratory settings and should be handled and stored with proper care and caution to avoid potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 144461-19-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,4,6 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 144461-19:
(8*1)+(7*4)+(6*4)+(5*4)+(4*6)+(3*1)+(2*1)+(1*9)=118
118 % 10 = 8
So 144461-19-8 is a valid CAS Registry Number.
144461-19-8Relevant articles and documents
Synthesis of acyclic nucleoside derivatives
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, (2008/06/13)
Methods and novel intermediates of the formula: wherein R6 and R7 are lower alkyl or benzyl or R6 and R7 taken together are —CH2CH2—, —CH2CH2CH2— or —CH2CH2CH2CH2CH2—, R8 is C1-C21 alkyl or a C2-C21 monounsaturated alkenyl, which may optionally be substituted with substitution substituents independently selected from the group consisting of hydroxy, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkoxy C1-C6 alkyl, C1-C6 alkanoyl, amino, halo, cyano, azido, oxo, mercapto and nitro, and R9 is an alcohol protecting group. The intermediates are useful for the preparation of acyclic nucleoside derivatives of the formula: where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a —C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.
Synthesis of chiral 3-substituted γ-lactones and 9-furanosyl-adenine from (R)-2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate prepared by lipase-catalyzed reaction
Terao,Akamatsu,Achiwa
, p. 823 - 825 (2007/10/02)
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