144750-52-7 Usage
Description
CLOPIDOGREL RELATED COMPOUND B (20 MG) (METHYL(+/-)-(O-CHLOROPHENYL)-4,5-DIHYDROTHIE-NO[2,3-C]PYRIDINE-6(7H)-ACETATE, HYDROCHLORIDE) is a tetrahydrothienopyridine derivative with a molecular weight of 20 mg. It is a white to off-white solid and is known for its role as an inhibitor of angiogenesis, a process that plays a crucial role in the growth and metastasis of various types of cancer.
Uses
Used in Pharmaceutical Industry:
CLOPIDOGREL RELATED COMPOUND B (20 MG) (METHYL(+/-)-(O-CHLOROPHENYL)-4,5-DIHYDROTHIE-NO[2,3-C]PYRIDINE-6(7H)-ACETATE, HYDROCHLORIDE) is used as an inhibitor of angiogenesis for the development of potential anti-cancer drugs. By inhibiting angiogenesis, it can help in the treatment of various types of cancer by preventing the formation of new blood vessels that supply nutrients to the tumor cells, thereby limiting their growth and spread.
Used in Research and Development:
In the field of research and development, CLOPIDOGREL RELATED COMPOUND B (20 MG) is utilized as a valuable compound for studying the mechanisms of angiogenesis and its role in cancer progression. CLOPIDOGREL RELATED COMPOUND B (20 MG) (METHYL(+/-)-(O-CHLOROPHENYL)-4,5-DIHYDROTHIE-NO[2,3-C]PYRIDINE-6(7H)-ACETATE, HYDROCHLORIDE) can be used to develop new therapeutic strategies and explore the potential of tetrahydrothienopyridine derivatives in cancer treatment.
Used in Quality Control and Standardization:
CLOPIDOGREL RELATED COMPOUND B (20 MG) is also used in the pharmaceutical industry for quality control and standardization purposes. It serves as a reference compound to ensure the purity, potency, and consistency of clopidogrel, a widely used antiplatelet drug, and its related compounds in the manufacturing process.
Check Digit Verification of cas no
The CAS Registry Mumber 144750-52-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,7,5 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 144750-52:
(8*1)+(7*4)+(6*4)+(5*7)+(4*5)+(3*0)+(2*5)+(1*2)=127
127 % 10 = 7
So 144750-52-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H16ClNO2S.ClH/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-11-7-9-21-14(11)10-18;/h2-5,7,9,15H,6,8,10H2,1H3;1H
144750-52-7Relevant articles and documents
Synthesis and characterization of impurity B of S-(+)-clopidogrel bisulfate: An antiplatelet
Reddy, K. Tatendra,Kumar, K. Suneel,Omprakash,Dubey
, p. 1387 - 1396 (2013/05/22)
S-(+)-Clopidogrel bisulfate [(S-(+)-methyl 2-(2-chlorophenyl)-2-(6, 7-dihydrothieno[3, 2-c]pyridin-5(4H)-yl)acetate bisulfate)] is a platelet aggregation inhibitor drug. S-(+)-Clopidogrel bisulfate is prepared by different synthetic approaches in the literature. In almost all the approaches the major impurities known in the literature (A, B, and C) are also listed in the U.S. pharmacopoeia. The control of these pharmaceutical impurities is currently a critical issue to the pharmaceutical industry. In this article, a description of these impurities and their origins in the S-(+)-clopidogrel bisulfate process are presented along with the preparation of impurity B.