145513-97-9 Usage
Description
(S)-(+)-2-PHENYL-N-(TRIFLUOROACETYL)-GLYCINE METHYL ESTER, 97 is a chemical compound with a molecular formula of C12H12F3NO3. It is a trifluoroacetyl derivative of the amino acid glycine, known for its use as a reagent in various chemical reactions and synthesis processes. (S)-(+)-2-PHENYL-N-(TRIFLUOROACETYL)-GLY CINE METHYL ESTER, 97 is commonly utilized in the production of pharmaceuticals, agrochemicals, and other fine chemicals. With a purity level of 97%, it is a high-quality and highly effective chemical reagent that is used in research and development laboratories, as well as in the industrial production of various compounds. It is crucial to handle and store this compound according to safety guidelines and regulatory requirements to ensure safe and effective use.
Uses
Used in Pharmaceutical Industry:
(S)-(+)-2-PHENYL-N-(TRIFLUOROACETYL)-GLYCINE METHYL ESTER, 97 is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its application in this industry is due to its ability to facilitate the creation of new drugs and improve the effectiveness of existing medications.
Used in Agrochemical Industry:
In the agrochemical industry, (S)-(+)-2-PHENYL-N-(TRIFLUOROACETYL)-GLYCINE METHYL ESTER, 97 is used as a building block for the development of new agrochemicals. Its use in this industry is attributed to its role in enhancing the properties of agrochemicals, such as increasing their effectiveness and reducing environmental impact.
Used in Fine Chemicals Production:
(S)-(+)-2-PHENYL-N-(TRIFLUOROACETYL)-GLYCINE METHYL ESTER, 97 is also used as a reagent in the production of fine chemicals. Its application in this area is due to its versatility in chemical reactions, allowing for the creation of a wide range of high-quality specialty chemicals.
Used in Research and Development Laboratories:
(S)-(+)-2-PHENYL-N-(TRIFLUOROACETYL)-GLY CINE METHYL ESTER, 97 is used as a research tool in laboratories for the development of new chemical processes and the synthesis of novel compounds. Its use in research and development is driven by its high purity and effectiveness as a reagent, enabling scientists to explore new avenues in chemical research.
Used in Industrial Production of Compounds:
(S)-(+)-2-PHENYL-N-(TRIFLUOROACETYL)-GLYCINE METHYL ESTER, 97 is employed in the industrial production of various compounds, thanks to its high purity and reactivity. Its use in this context is aimed at improving the efficiency and quality of the compounds produced, leading to better performance and application in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 145513-97-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,5,1 and 3 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 145513-97:
(8*1)+(7*4)+(6*5)+(5*5)+(4*1)+(3*3)+(2*9)+(1*7)=129
129 % 10 = 9
So 145513-97-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H10F3NO3/c1-18-9(16)8(7-5-3-2-4-6-7)15-10(17)11(12,13)14/h2-6,8H,1H3,(H,15,17)/t8-/m0/s1
145513-97-9Relevant articles and documents
Synthesis, characterization and enantioselective free radical reductions of (1R,2S,5R)-menthyldiphenylgermane and its enantiomer
Zeng, Le,Dakternieks, Dainis,Duthie, Andrew,Perchyonok, Tamara,Schiesser, Carl
, p. 2547 - 2554 (2004)
a- a- a- (1R,2S,5R)-Menthyldiphenylgermane and its enantiomer have been prepared in a few steps from germanium tetrachloride. The initial step in this sequence, namely the reaction between germanium tetrachloride and menthylmagnesium chloride, produces menthylgermanium trichloride, which is the exclusive product of this Grignard reaction, presumably due to the bulk of the menthyl group. When used at a low temperature (-78°C) and in conjunction with Lewis acids, such as magnesium salts, these chiral germanes are capable of reducing ester functionalized radicals in high enantioselectivity, but in low-moderate yield. For example, (R)-naproxen ethyl ester was obtained in 15% yield and 99% ee by reaction in toluene of 2-bromonaproxen ethyl ester with (1R,2S,5R)-menthyldiphenylgermane in toluene at -78°C in the presence of magnesium bromide. At 80°C, (1R,2S,5R)-menthyldiphenylgermane reacted with primary alkyl radicals with a rate constant of 1.02×106 M-1 s-1. Kinetic studies reveal the Arrhenius expression for this reaction to be: log(k/M-1 s-1) = (11.1 ± 0.4) - (34.6±3.1)/θ where θ=2.3RT kJ mol-1.
Substituted pteridines for the treatment of inflammatory diseases
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Page/Page column 7, (2010/11/08)
The invention relates to new pteridines which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers, as
ORGANOGERMANIUM COMPOUNDS AND METHODS FOR THEIR USE
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Page/Page column 28; 31, (2010/02/06)
The invention provides a method for enantioselectively reducing a prochiral carbon centred radical having one or more electron donor groups attached directly to the central prochiral carbon atom of the radical, and/or attached to a carbon atom within 1 to 4 atoms of the central prochiral carbon atom, comprising treating said radical with a chiral non-racemic organogermanium hydride in the presence of a Lewis acid. The invention also provides a novel class of chiral non-racemic organogermanium hydrides and a method of preparing chiral non-racemic organogermanium compounds.
