14690-00-7 Usage
Description
2-BENZYLOXY-1,3-PROPANEDIOL, also known as a glycerol derivative, is an organic compound with the molecular formula C10H14O4. It features a propanediol backbone with a benzyloxy group attached to the second carbon, which contributes to its unique chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
2-BENZYLOXY-1,3-PROPANEDIOL is used as a key intermediate compound for the synthesis of glycerides and their phosphonate analogs. These synthesized compounds have demonstrated potent inhibitory effects on lipase, an enzyme that plays a crucial role in the breakdown of fats in the body. By inhibiting lipase, these glycerides and phosphonate analogs can potentially be utilized in the development of treatments for obesity and related metabolic disorders.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-BENZYLOXY-1,3-PROPANEDIOL can be employed as a versatile building block for the creation of various complex organic molecules. Its unique structure allows for further functionalization and modification, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Research and Development:
2-BENZYLOXY-1,3-PROPANEDIOL also finds application in research and development laboratories, where it can be used to study the structure-activity relationships of glycerol derivatives and their potential biological activities. This knowledge can be applied to the design and development of new drugs and therapeutic agents with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 14690-00-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,6,9 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 14690-00:
(7*1)+(6*4)+(5*6)+(4*9)+(3*0)+(2*0)+(1*0)=97
97 % 10 = 7
So 14690-00-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O3/c11-6-10(7-12)13-8-9-4-2-1-3-5-9/h1-5,10-12H,6-8H2
14690-00-7Relevant articles and documents
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Cunningham,J. et al.
, p. 1191 - 1196 (1964)
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Polycarbonate and poly(carbonate-ester)s synthesized from biocompatible building blocks of glycerol and lactic acid
Ray III, William C.,Grinstaff, Mark W.
, p. 3557 - 3562 (2003)
The synthesis and characterization of a polycarbonate of glycerol and poly(carbonate-ester)s of glycerol and L-lactic acid are reported. These new polymers possess a hydrolyzable backbone, tunable hydrophobic/hydrophilic properties, and functionalizable p
BORON CLUSTER-COUPLED COMPOUND
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Paragraph 0178; 0186-0188, (2021/03/05)
To provide a novel boron-containing compound which increases intratumorous accumulation and tumor retention, and is efficiently taken into a tumor cell.SOLUTION: The present invention relates to a compound represented by formula (I) in the figure or a salt thereof. [In the formula, X represents a divalent to pentavalent organic group; Y represents a linker structure; R represents a monovalent group comprising boron clusters; and n represents 2, 3, 4 or 5.SELECTED DRAWING: None
Regioselective Ring-Opening of Glycidol to Monoalkyl Glyceryl Ethers Promoted by an [OSSO]-FeIII Triflate Complex
Monica, Francesco Della,Ricciardi, Maria,Proto, Antonio,Cucciniello, Raffaele,Capacchione, Carmine
, p. 3448 - 3452 (2019/08/01)
A FeIII-triflate complex, bearing a bis-thioether-di-phenolate [OSSO]-type ligand, was discovered to promote the ring-opening of glycidol with alcohols under mild reaction conditions (0.05 mol % catalyst and 80 °C). The reaction proceeded with high activity (initial turnover frequency of 1680 h?1 for EtOH) and selectivity (>95 %) toward the formation of twelve monoalkyl glyceryl ethers (MAGEs) in a regioselective fashion (84–96 % yield of the non-symmetric regioisomer). This synthetic approach allows the conversion of a glycerol-derived platform molecule (i.e., glycidol) to high-value-added products by using an Earth-crust abundant metal-based catalyst.
