68728-34-7

Basic information

• Product Name: 5-(benzyloxy)-2-phenyl-1,3-dioxane
• CAS NO: 68728-34-7
• Molecular Formula: C₁₇H₁₈O₃
• Molecular Weight: 270.323
• Mol File: 68728-34-7.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 398.3°C at 760 mmHg
• Flash Point: 135.2°C
• Density: 1.15g/cm³
• Vapor Pressure: 3.42E-06mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 5-(benzyloxy)-2-phenyl-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzyloxy)-2-phenyl-1,3-dioxane(68728-34-7)
• EPA Substance Registry System: 5-(benzyloxy)-2-phenyl-1,3-dioxane(68728-34-7)

Safety Data

• Hazardous Substances Data: 68728-34-7(Hazardous Substances Data)

Usage

General Description

5-(benzyloxy)-2-phenyl-1,3-dioxane is a chemical compound with the molecular formula C16H16O3. It is an organic compound that belongs to the class of dioxane derivatives, which are cyclic organic compounds containing a 1,3-dioxane moiety. This specific compound contains a benzyl group and a phenyl group attached to the 2 and 3 positions of the dioxane ring, respectively. It is commonly used in organic synthesis and pharmaceutical research as a building block for the creation of more complex compounds. Additionally, it has potential applications in the development of new materials and pharmaceutical drugs due to its unique chemical structure and properties.

Upstream product

• 100-39-0 benzyl bromide 
• 1708-40-3 2-phenyl-[1,3]dioxan-5-ol 
• 100-44-7 benzyl chloride 
• 100-52-7 benzaldehyde 

Downstream Products

• 14690-00-7 2-O-benzylglycerol 
• 76163-48-9 2-O-benzyl-1,3-di-O-palmitoyl-rac-glycerol 
• 76163-43-4 2-O-benzyl-1,3-di-O-stearoyl-rac-glycerol 
• 20441-81-0 α--β-benzyl-glycerin 
• 20441-82-1 α,γ-Bis--β-benzyl-glycerin 
• 20441-83-2 Benzyl-(β,γ-distearoyl-glycerin)-(β-benzyl-γ-N-benzyloxycarbonyl-glycyl-glycerin)-phosphat 
• 47916-93-8 Octadecanoic acid 2-{[2-benzyloxy-3-(2-benzyloxycarbonylamino-acetoxy)-propoxy]-hydroxy-phosphoryloxy}-1-octadecanoyloxymethyl-ethyl ester 
• 927814-91-3 2-(benzyloxy)-1,3-bis[(diisopropoxyphosphoryl)methoxy]propane 
• 19945-19-8 2-(benzyloxy)propane-1,3-diyl bis(4-methylbenzenesulfonate) 
• 86629-66-5 5-(benzyloxy)-1,3-dioxan-2-one 
• 18678-94-9 2-benzyloxy-3-hexadecyloxy-1-propanol 
• 18678-98-3 Rac_. 1-O-Hexadecyl-2-O-benzylglycero-3-phosphocholin 
• 105543-67-7 2-O-Benzyl-glycerin-1-iodhydrin 
• 98561-90-1 3-hydroxy-2(S)-O-benzylglycerol p-methylbenzenesulfonate 

Relevant articles and documents

New amphiphilic polycarbonates with side functionalized cholesteryl groups as biomesogenic units: synthesis, structure and liquid crystal behavior

The synthesis of four new amphipathic copolymers with side functionalized-cholesterol based aliphatic polycarbonates is described through the ring-opening polymerization and coupling reaction. The chemical structures, liquid crystal (LC) behavior, and thermal stability of the chiral monomers and copolymers obtained in this study were characterized using Fourier transform infrared (FT-IR) spectroscopy, proton nuclear magnetic resonance (1H NMR) spectroscopy, gel permeation chromatography (GPC), polarizing optical microscopy (POM), differential scanning calorimetry (DSC), X-ray diffraction (XRD), and thermogravimetric analysis (TGA) measurements. The effect of the spacer length on the molecular interaction and mesophase of the chiral monomers and copolymers was investigated. It was found that chiral monomers with longer spacer seemed beneficial for the formation of mesophases, and the additional ordering on polymerization caused mesophases to be more ordered than for the corresponding monomers. The LC copolymers all revealed a smectic A phase with an interdigitated molecular arrangement. The results seemed to show a decreased tendency toward the glass transition temperature, and isotropic temperature for the LC copolymers by increasing the spacer length. In addition, four LC copolymers had a good thermal stability.

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

3-hydroxyl oxygen heterocyclic butane preparation method of compound

The invention discloses a synthetic method of a 3-hydroxy oxetane compound shown as a formula I. The method provided by the invention employs substituted glycerol I-1 as a raw material, which is subjected to condensation with aldehydes and ketones compounds to obtain a compound I-2; the I-2 is subjected to R2 protection to obtain a compound I-3; the compound I-3 is subjected to removal of aldehydes and ketones protecting groups to obtain a compound I-4; the compound I-4 is subjected to intramolecular cyclization to obtain a compound I-5; and the compound I-5 is subjected to removal of R2 protection to obtain a target compound I. Although the method has a long route, the reaction conditions are mild, and the post treatment and detection are convenient; therefore, the method is suitable for industrialized production.