147283-76-9 Usage
Description
ETHYL (3-NITRO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE is a chemical compound characterized by its molecular formula C9H9NO5. It is a yellow solid that serves as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Known by its trade name Ethyl 3-nitro-2-oxo-1,2-dihydropyridylacetate, this compound is utilized as a building block in organic synthesis, enabling the production of a diverse array of derivatives through various chemical reactions.
Uses
Used in Pharmaceutical Industry:
ETHYL (3-NITRO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE is used as an intermediate in the synthesis of medicines, playing a crucial role in the development and manufacturing of various pharmaceutical products.
Used in Agrochemical Industry:
ETHYL (3-NITRO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE is also utilized as an intermediate in the production of agrochemicals, contributing to the development of products designed to enhance agricultural productivity and manage pests.
Used in Organic Synthesis:
ETHYL (3-NITRO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE is employed as a building block in organic synthesis, allowing for the creation of a wide range of derivatives through chemical reactions, which can be applied across different industries and research fields.
Check Digit Verification of cas no
The CAS Registry Mumber 147283-76-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,2,8 and 3 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 147283-76:
(8*1)+(7*4)+(6*7)+(5*2)+(4*8)+(3*3)+(2*7)+(1*6)=149
149 % 10 = 9
So 147283-76-9 is a valid CAS Registry Number.
147283-76-9Relevant articles and documents
A facile and efficient method for the synthesis of novel pyridone analogues by aminolysis of an ester under solvent-free conditions
Karis, N. David,Loughlin, Wendy A.,Jenkins, Ian D.
, p. 12303 - 12309 (2008/03/12)
A series of 15 pure novel N-alkylated pyridone derivatives have been synthesized in 73-96% yields on treatment of ethyl (2-pyridone)acetates with structurally diverse amines in an efficient aminolysis procedure under 'solvent-free' conditions.
Design, synthesis, and structure-activity relationships of unsubstituted piperazinone-based transition state factor Xa inhibitors
Huang, Wenrong,Naughton, Mary Ann,Yang, Hua,Su, Ting,Dam, Suiko,Wong, Paul W.,Arfsten, Ann,Edwards, Susan,Sinha, Uma,Hollenbach, Stanley,Scarborough, Robert M.,Zhu, Bing-Yan
, p. 723 - 728 (2007/10/03)
A series of novel transition state factor Xa inhibitors containing a variety of lactam ring systems as central templates was synthesized in an expedient manner and allowed for a great deal of structural variability. Among them, the piperazinone-based inhibitors were found to be not only active against factor Xa but also selective over thrombin. Optimization of the P4 moiety yielded several potent compounds with IC50 below 1 nM against factor Xa.
Aromatic heterocyclic derivatives as enzyme inhibitors
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Page column 46-47, (2010/02/04)
The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
