147637-25-0

Basic information

• Product Name: 7-Chloro-1-(2-methoxy-phenyl)-1,3-dihydro-isobenzofuran-1-ol
• CAS NO: 147637-25-0
• Molecular Weight: 276.719
• Mol File: 147637-25-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-Chloro-1-(2-methoxy-phenyl)-1,3-dihydro-isobenzofuran-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloro-1-(2-methoxy-phenyl)-1,3-dihydro-isobenzofuran-1-ol(147637-25-0)
• EPA Substance Registry System: 7-Chloro-1-(2-methoxy-phenyl)-1,3-dihydro-isobenzofuran-1-ol(147637-25-0)

Safety Data

• Hazardous Substances Data: 147637-25-0(Hazardous Substances Data)

Upstream product

• 70097-45-9 7-chloroisobenzofuran-1(3H)-one 
• 31600-86-9 2-methoxyphenyllithium 
• 147637-19-2 2-Chloro-6-hydroxymethyl-N-phenyl-benzamide 
• 146516-81-6 7-chloro-3-hydroxy-2-phenyl-2,3-dihydro-1H-isoindol-1-one 
• 6833-13-2 2-chlorobenzanilide 

Relevant articles and documents

Application of organolithium and related reagents in synthesis. Part 13. Synthetic strategies based on aromatic metallation. A concise regiospecific conversion of benzoic acids into 4-hydroxy-1-arylnaphthalenes

The synthesis of the 3-unsubstituted phthalides (5) and their conversion into 1-hydroxy-1-arylphthalans (8), very useful precursors of isobenzofurans (10) and subsequent cycloaddition of them to dimethyl acetylenedicarboxylate as a way of regiospecific transformation of benzoic acids into dimethyl 4-hydroxy-1-(2-methoxyphenyl)naphthalene-2,3-dicarboxylates (12) (biaryls highly substituted around the axis), is described.