70097-45-9 Usage
General Description
7-Chlorophthalide is a chemical compound that forms part of the phthalide family. It is a colorless crystalline solid and has the chemical formula C8H4Cl2O2. 7-Chlorophthalide is used as an intermediate in organic synthesis, especially in the pharmaceutical industry where it is utilized in the production of various drugs. 7-Chlorophthalide is known for its importance in the synthesis of antidepressants like citalopram, which is used in the treatment of major depression. The presence of the chlorine atom in the molecule facilitates various reaction pathways during synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 70097-45-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,0,9 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 70097-45:
(7*7)+(6*0)+(5*0)+(4*9)+(3*7)+(2*4)+(1*5)=119
119 % 10 = 9
So 70097-45-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5ClO2/c9-6-3-1-2-5-4-11-8(10)7(5)6/h1-3H,4H2
70097-45-9Relevant articles and documents
Application of organolithium and related reagents in synthesis. Part 13. Synthetic strategies based on aromatic metallation. A concise regiospecific conversion of benzoic acids into 4-hydroxy-1-arylnaphthalenes
Epsztajn, Jan,Jozwiak, Andrzej,Szczesniak, Aleksandra K.
, p. 929 - 938 (2007/10/02)
The synthesis of the 3-unsubstituted phthalides (5) and their conversion into 1-hydroxy-1-arylphthalans (8), very useful precursors of isobenzofurans (10) and subsequent cycloaddition of them to dimethyl acetylenedicarboxylate as a way of regiospecific transformation of benzoic acids into dimethyl 4-hydroxy-1-(2-methoxyphenyl)naphthalene-2,3-dicarboxylates (12) (biaryls highly substituted around the axis), is described.
