154027-28-8

Basic information

• Product Name: 3,4-dihemisuccinylnivalenol
• CAS NO: 154027-28-8
• Molecular Weight: 512.468
• Mol File: 154027-28-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,4-dihemisuccinylnivalenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihemisuccinylnivalenol(154027-28-8)
• EPA Substance Registry System: 3,4-dihemisuccinylnivalenol(154027-28-8)

Safety Data

• Hazardous Substances Data: 154027-28-8(Hazardous Substances Data)

Upstream product

• 108-30-5 succinic acid anhydride 
• 23282-20-4 nivalenol 
• 6022-19-1 4β,15-Diacetylnivalenol 

Relevant articles and documents

Preparation, Purification, and NMR Spectra of Some Mono- and Dihemisuccinates of the Trichothecene Mycotoxin Nivalenol

4,15-Diacetylnivalenol (DANIV) was produced in liquid culture and purified by fractionation over silica followed by preparative liquid chromatography.Hydrolysis gave nivalenol (NIV), a trichothecene mycotoxin found as a common contaminant in grain grown in the North Island of New Zealand.Reaction of NIV with succinic anhydride in the presence of n-butylboronic acid and (dimethylamino)pyridine produced a mixture of three mono- and two dihemisuccinates.These were separated by semipreparative HPLC.The major product was 3-hemisuccinyl-NIV (3-HS-NIV).Other products were 4-HS-NIV, 15-HS-NIV, 3,4-diHS-NIV, and 3,15-diHS-NIV. 3-HS-NIV was also produced by enzymatic hydrolysis of 3-HS-DANIV.