157666-32-5

Basic information

• Product Name: 4-chloro-7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-5-methyl-7H-pyrrolo<2,3-d>pyrimidine
• Synonyms: 4-chloro-7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-5-methyl-7H-pyrrolo<2,3-d>pyrimidine
• CAS NO: 157666-32-5
• Molecular Weight: 519.985
• Mol File: 157666-32-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-chloro-7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-5-methyl-7H-pyrrolo<2,3-d>pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-5-methyl-7H-pyrrolo<2,3-d>pyrimidine(157666-32-5)
• EPA Substance Registry System: 4-chloro-7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-5-methyl-7H-pyrrolo<2,3-d>pyrimidine(157666-32-5)

Safety Data

• Hazardous Substances Data: 157666-32-5(Hazardous Substances Data)

Upstream product

• 452-51-7 D-2-deoxyribose 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 4330-34-1 methyl 3,5-di-O-toluoyl-2-deoxy-D-ribofuranose 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 22276-95-5 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 1618-36-6 4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine 

Relevant articles and documents

Synthesis of certain 5-substituted 2'-deoxytubercidin derivatives

The synthesis of the 7-deaza-2'-deoxy-adenine derivatives 7b-d with chloro, bromo, or methyl substituents at C(5) is described. Glycosylation of the 5-substituted 4-chloropyrrolo[2,3-d]pyrimidines 4b-d with 2-deoxy-3,5-di-O-(4-toluoyl)-α-D-erythro-pentofuranosyl chloride (3) gave the β-D-nucleosides 5b-d, exclusively. They were deblocked (→ 6b-d) and converted into the tubercidin derivatives 7b-d.