158980-66-6

Basic information

• Product Name: (3R,4R)-tert-butyl-3-(4-(benzyloxy)benzamido)-4-(3,5-bis(benzyloxy)-4-(2-(benzyloxy)-6-(benzyloxycarbonyl)benzoyl)benzoyloxy)azepane-1-carboxylate
• Synonyms: (3R,4R)-tert-butyl-3-(4-(benzyloxy)benzamido)-4-(3,5-bis(benzyloxy)-4-(2-(benzyloxy)-6-(benzyloxycarbonyl)benzoyl)benzoyloxy)azepane-1-carboxylate
• CAS NO: 158980-66-6
• Molecular Weight: 1101.26
• Mol File: 158980-66-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3R,4R)-tert-butyl-3-(4-(benzyloxy)benzamido)-4-(3,5-bis(benzyloxy)-4-(2-(benzyloxy)-6-(benzyloxycarbonyl)benzoyl)benzoyloxy)azepane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-tert-butyl-3-(4-(benzyloxy)benzamido)-4-(3,5-bis(benzyloxy)-4-(2-(benzyloxy)-6-(benzyloxycarbonyl)benzoyl)benzoyloxy)azepane-1-carboxylate(158980-66-6)
• EPA Substance Registry System: (3R,4R)-tert-butyl-3-(4-(benzyloxy)benzamido)-4-(3,5-bis(benzyloxy)-4-(2-(benzyloxy)-6-(benzyloxycarbonyl)benzoyl)benzoyloxy)azepane-1-carboxylate(158980-66-6)

Safety Data

• Hazardous Substances Data: 158980-66-6(Hazardous Substances Data)

Upstream product

• 1486-50-6 4-(benzyloxy)benzoic acid chloride 
• 158980-65-5 1,1-dimethylethyl (3R)-trans-hexahydro-4-hydroxy-3-{[4-(phenylmethoxy)benzoyl]amino}-1H-azepine-1-carboxylate 
• 167832-93-1 3-Benzyloxy-2-(2,6-bis-benzyloxy-4-chlorocarbonyl-benzoyl)-benzoic acid benzyl ester 
• 158980-64-4 (3S,4R)-3-Amino-4-hydroxy-azepan-2-one 
• 198419-15-7 (3R,4R)-3-amino-4-hydroxyazepane-1-carboxylic acid tert butyl ester 
• 150989-57-4 (3R,4R)-3-amino-4-hydroxyazepine 
• 158980-63-3 1,1-dimethylethyl 4-<6-(benzyloxy)-2-<(benzyloxy)carbonyl>benzoyl>-3,5-bis(benzyloxy)benzoate 
• 158980-59-7 1,1-dimethylethyl 2-bromo-3-(benzyloxy)benzyl 2,5-bis(benzyloxy)-1,4-dibenzoate 
• 158980-62-2 3-Benzyloxy-2-[2,6-dibenzyloxy-4-(1,1-dimethylethoxycarbonyl)-benzoyl]benzoic acid 
• 158980-61-1 1,1-dimethylethyl 3,5-bis(benzyloxy)-4-<6-(benzyloxy)-2-formylbenzoyl>benzoate 
• 158980-60-0 1,1-dimethylethyl 3,5-bis(benzyloxy)-4-<6-(benzyloxy)-2-(hydroxymethyl)benzoyl>benzoate 
• 158980-58-6 3,5-Bis-benzyloxy-4-chlorocarbonyl-benzoic acid tert-butyl ester 
• 158980-56-4 2,6-bis(benzyloxy)-4-<(1,1-dimethylethoxy)carbonyl>benzoic acid 
• 158585-09-2 benzyl 4-bromo-3,5-bis(benzyloxy)benzoate 

Relevant articles and documents

Divergent response of homologous ATP sites to stereospecific ligand fluorination for selectivity enhancement

Acquiring a divergent response from homologous protein domains is essential for selective ligand-protein interactions. Stereospecific fluorination of (?)-balanol, an ATP mimic, uncovers a new source of selectivity from integrated chemical and conformational perturbation that differentiates homologous sites by the level of congruency in their response to local and remote fluorine effects.

Total Synthesis of (-)-Balanol

(-)-Balanol, a fungal metabolite with potent protein kinase C inhibitory properties, has been prepared in a total synthesis which makes use of an anionic homo-Fries rearrangement approach to the benzophenone subunit and in which the azepane subunit is obt