15951-99-2

Basic information

• Product Name: (1R,2S)-1,2-Dichloro-1,2-diphenylethane
• Synonyms: (1R,2S)-1,2-Dichloro-1,2-diphenylethane;Nsc405531
• CAS NO: 15951-99-2
• Molecular Formula: C₁₄H₁₂Cl₂
• Molecular Weight: 251.1511
• Mol File: 15951-99-2.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 325.7°Cat760mmHg
• Flash Point: 163.6°C
• Appearance: /
• Density: 1.212g/cm³
• CAS DataBase Reference: (1R,2S)-1,2-Dichloro-1,2-diphenylethane(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-1,2-Dichloro-1,2-diphenylethane(15951-99-2)
• EPA Substance Registry System: (1R,2S)-1,2-Dichloro-1,2-diphenylethane(15951-99-2)

Safety Data

• Hazardous Substances Data: 15951-99-2(Hazardous Substances Data)

Usage

Description

(1R,2S)-1,2-Dichloro-1,2-diphenylethane is a chiral chemical compound with the molecular formula C14H12Cl2. It is characterized by its non-superimposable mirror images, which makes it a valuable reagent in organic synthesis for the formation of chiral molecules.

Uses

Used in Organic Synthesis:
(1R,2S)-1,2-Dichloro-1,2-diphenylethane is used as a reagent in organic synthesis for the formation of chiral molecules. Its unique chiral properties allow for the creation of complex organic compounds with specific stereochemistry.
Used in Pharmaceutical Production:
(1R,2S)-1,2-Dichloro-1,2-diphenylethane serves as a building block in the production of pharmaceuticals. Its ability to form chiral molecules is crucial in the development of drugs with desired biological activities and reduced side effects.
Used in Agrochemical Production:
(1R,2S)-1,2-Dichloro-1,2-diphenylethane is also used as a building block in the production of agrochemicals, where chiral molecules can be essential for the effectiveness and selectivity of these products.
Used in Material Development:
(1R,2S)-1,2-Dichloro-1,2-diphenylethane has been studied for its potential use in the development of new materials, leveraging its unique properties to create innovative substances with specific applications.
Used in Catalysis Reactions:
As a ligand in catalysis reactions, (1R,2S)-1,2-Dichloro-1,2-diphenylethane can enhance the efficiency and selectivity of various chemical processes, contributing to the advancement of synthetic chemistry.
It is important to handle (1R,2S)-1,2-Dichloro-1,2-diphenylethane with caution, as it is toxic if ingested or inhaled and can cause skin and eye irritation. Proper safety measures should be taken during its use in research and industrial applications.

Upstream product

• 98-87-3 benzylidene dichloride 
• 588-59-0 stilbene 
• 492-70-6 1,2-diphenyl-1,2-ethanediol 
• 655-48-1 DL-1,2-diphenylethane-1,2-diol 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 645-49-8 cis-stilben 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 100-52-7 benzaldehyde 
• 56-23-5 tetrachloromethane 
• 917-64-6 methyl magnesium iodide 
• 60-29-7 diethyl ether 
• 947-91-1 Diphenylacetaldehyde 
• 579-43-1 (1S,2R)-1,2-diphenylethane-1,2-diol 
• 13440-24-9 anti-1,2-dibromo-1,2-diphenylethane 

Downstream Products

• 1460-06-6 (1-chloroethene-1,2-diyl)dibenzene 
• 492-70-6 1,2-diphenyl-1,2-ethanediol 
• 655-48-1 DL-1,2-diphenylethane-1,2-diol 
• 3682-07-3 anti-acetic acid 2-acetoxy-1,2-diphenyl-ethyl ester 
• 3682-07-3 syn-acetic acid 2-acetoxy-1,2-diphenyl-ethyl ester 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 948-99-2 α-chloro-(Z)-stilbene 
• 501-65-5 diphenyl acetylene 
• 948-98-1 (E)-α-chlorostilbene 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 645-49-8 cis-stilben 
• 588-59-0 stilbene 
• 7647-01-0 hydrogenchloride 
• 17547-17-0 1,1,2-trichloro-1,2-diphenyl ethane 

Relevant articles and documents

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Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand

Chlorination with chlorine is straightforward, highly reactive, and versatile, but it has significant limitations. In this Letter, we introduce a protocol that could combine the efficiency of electrochemical transformation and the high reactivity of chlorine. By utilizing Cl3CCN as the chloride source, donating up to all three chloride atom, the reaction could generate and consume the chlorine in situ on demand to achieve the chlorination of aromatic compounds and electrodeficient alkenes.

Preparation method of dichloro addition product of aromatic olefin under visible light catalysis

The invention relates to a preparation method of a dichloro addition product of aromatic olefin under visible light catalysis. The preparation method comprises the following step: by taking aromatic olefin as a substrate and copper chloride with visible light absorption capability as a chlorine source, reacting in an organic solvent under the irradiation of visible light in an inert atmosphere toobtain a dichloro addition product of the aromatic olefin after the reaction is completed. The aromatic olefin comprises a carbon-carbon double bond and an aryl group connected with the carbon-carbondouble bond through a covalent bond. Visible light is used for providing energy required by the reaction, copper chloride with visible light absorption capacity and a reaction substrate are used for photoinduction of chlorine atom transfer and initiation of an addition reaction to obtain a dichloro addition product, and the method is mild in reaction condition, simple and convenient to operate andwide in universality of the reaction substrate.

Vicinal dichlorination of olefins using NH4Cl and oxone

A mild and efficient protocol for the preparation of 1,2-dichloroalkane derivatives from olefins using NH4Cl and Oxone at room temperature is described. A variety of terminal, internal, and cyclic alkenes reacted smoothly to give the corresponding dichlorinated products in good to excellent yields. Moreover, 1,2-disubstituted symmetrical and unsymmetrical olefins dichlorinated with moderate to excellent diastereoselectivity. This method precludes the use of acidic additives and transition metals in the synthesis of vicinal dichlorides.