579-43-1

Basic information

• Product Name: meso-1,2-Diphenyl-1,2-ethanediol
• Synonyms: 1,2-Ethanediol, 1,2-diphenyl-, (R*,S*)-;1,2-Ethanediol, 1,2-diphenyl-, meso-;meso-Stilbene glycol;1,2-DIPHENYL-1,2-ETHANEDIOL;MESO-1,2-DIPHENYLETHYLENE GLYCOL;MESO-1,2-DIPHENYL-1,2-ETHANEDIOL;MESO-HYDROBENZOIN;HYDROBENZOIN MESO
• CAS NO: 579-43-1
• Molecular Formula: C₁₄H₁₄O₂
• Molecular Weight: 214.26
• EINECS: 207-758-3
• Mol File: 579-43-1.mol
• Article Data: 488

Chemical Properties

• Melting Point: 137-139 °C(lit.)
• Boiling Point: 373 °C at 760 mmHg
• Flash Point: 179.8 °C
• Appearance: White/Crystalline Powder
• Density: 1.193 g/cm³
• Vapor Pressure: 3.18E-06mmHg at 25°C
• Refractive Index: 1.624
• Storage Temp.: 2-8°C
• Solubility: Soluble in hot alcohol or chloroform.
• PKA: 13.38±0.20(Predicted)
• Merck: 14,4777
• BRN: 2050814
• CAS DataBase Reference: meso-1,2-Diphenyl-1,2-ethanediol(CAS DataBase Reference)
• NIST Chemistry Reference: meso-1,2-Diphenyl-1,2-ethanediol(579-43-1)
• EPA Substance Registry System: meso-1,2-Diphenyl-1,2-ethanediol(579-43-1)

Safety Data

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• WGK Germany: 3
• Hazardous Substances Data: 579-43-1(Hazardous Substances Data)

Usage

Description

meso-1,2-Diphenyl-1,2-ethanediol is a white crystalline powder with unique chemical properties that make it suitable for various applications across different industries.

Uses

Used in Chemical Synthesis:
meso-1,2-Diphenyl-1,2-ethanediol is used as a key intermediate for the preparation of trans-methyl meso-hydrobenzoin phosphite, which is an important compound in the chemical industry.
Used in Pharmaceutical Industry:
meso-1,2-Diphenyl-1,2-ethanediol is used as a chiral catalyst for the desymmetrization of meso-hydrobenzoin, a process that is crucial in the synthesis of various pharmaceutical compounds.
Used in Chemical Reactions:
meso-1,2-Diphenyl-1,2-ethanediol is used as a reactant in the conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide, which is a significant reaction in organic chemistry.

Purification Methods

meso-Hydrobenzoin [579-43-1] M 214.3, m 139o, 139-140o. Crystallise it from EtOH or water. [Beilstein 6 H 1003, 6 I 490, 6 II 967. 6 III 5429, 6 IV 6682.]

InChI:InChI=1/C14H14O2/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13-16H/t13-,14+

Upstream product

• 79-21-0 peracetic acid 
• 645-49-8 cis-stilben 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 530-36-9 2-amino-1,2-diphenylethanol 
• 496-45-7 glyoxal sulfate 
• 588-59-0 stilbene 
• 15951-99-2 1,2-dichloro-1,2-diphenylethane 
• 563-63-3 silver(I) acetate 
• 572-45-2 benzil dioxime 
• 1140-29-0 N-(2-aminoethyl)-N-phenylaniline 
• 60-29-7 diethyl ether 
• 677-22-5 tert-butylmagnesium chloride 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 671795-46-3 sec-butylmagnesium bromide 

Downstream Products

• 5457-14-7 8-methyl-2r,3c-diphenyl-1,4-dioxa-8-aza-spiro[4.5]decane 
• 451-40-1 phenyl benzyl ketone 
• 947-91-1 Diphenylacetaldehyde 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 15951-99-2 1,2-dichloro-1,2-diphenylethane 
• 13440-24-9 1,2-dibromo-1,2-diphenylethane 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 38270-63-2 2-benzhydryl-4,5-diphenyl-[1,3]dioxolane 
• 100-52-7 benzaldehyde 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 6067-45-4 4,4'-dinitrobenzil 
• 27797-53-1 4,5-diphenyl-[1,3]-dioxolan-2-one 
• 19455-94-8 (meso-bibenzyldiyl-(α.α'))-sulfite 
• 15951-99-2 meso-1,2-dichloro-1,2-diphenylethane 

Relevant articles and documents

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