16064-25-8

Basic information

• Product Name: 7-HYDROXY-1H-QUINAZOLIN-4-ONE
• Synonyms: 7-HYDROXY-1H-QUINAZOLIN-4-ONE;7-hydroxyquinazolin-4(1H)-one;4,7-Dihydroxyquinazoline
• CAS NO: 16064-25-8
• Molecular Formula: C8H6N2O2
• Molecular Weight: 162.15
• Mol File: 16064-25-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-HYDROXY-1H-QUINAZOLIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-HYDROXY-1H-QUINAZOLIN-4-ONE(16064-25-8)
• EPA Substance Registry System: 7-HYDROXY-1H-QUINAZOLIN-4-ONE(16064-25-8)

Safety Data

• Hazardous Substances Data: 16064-25-8(Hazardous Substances Data)

Usage

General Description

7-HYDROXY-1H-QUINAZOLIN-4-ONE is a chemical compound with the molecular formula C9H6N2O2. It belongs to the quinazolinone class of compounds and is a derivative of quinazoline. This chemical is known for its potential biological activities, including anti-tumor, anti-inflammatory, and antiviral properties. It has also been studied for its potential use in drug development and as a building block in organic synthesis. 7-HYDROXY-1H-QUINAZOLIN-4-ONE has shown promise in various research studies and continues to be of interest in the scientific community for its potential pharmacological applications.

Upstream product

• 16064-24-7 7-methoxyquinazoline-4(3H)-one 
• 4294-95-5 4-methoxyanthranilic acid 
• 90004-09-4 7-aminoquinazolin-4-one 
• 619-17-0 4-Nitroanthranilic acid 
• 446-32-2 4-fluoroanthranilic acid 
• 16499-57-3 7-fluoro-1H-quinazolin-4-one 
• 193002-14-1 7-(benzyloxy)quinazolin-4-ol 

Relevant articles and documents

Photoinduced homolytic decarboxylative acylation/cyclization of unactivated alkenes with α-keto acid under external oxidant and photocatalyst free conditions: access to quinazolinone derivatives

A novel and green strategy for the synthesis of acylated quinazolinone derivativesviaphoto-induced decarboxylative cascade radical acylation/cyclization of quinazolinone bearing unactivated alkenes has been developed. The protocol provides a novel route to access acyl radicals from α-keto acids through a self-catalyzed energy transfer process. Most importantly, the reaction proceeded smoothly without any external photocatalyst, additive or oxidant, and could be easily scaled-up in flow conditions with sunlight irradiation.

A in the aqueous phase under microwave conditions using halogenated benzamide fast synthesis of quinazoline compounds of the method

The invention discloses a in the aqueous phase under microwave conditions using halogenated benzamide fast synthesis of quinazoline compounds of the method, the use of palladium chloride to serve as the catalyst, in water under microwave heating conditions, neighbouring halogen benzamide with an isocyanate reaction to produce the quinazoline compounds of the method, the invention an environment-friendly, the operation is simple, cheap and safe, efficient process for producing quinazoline compounds of the method. Compared with the prior art, this method not only can be applied to a large number of functional groups, the productive rate is high, few by-products, and the operation is simple, safe, low cost, environmental protection.

Antiviral agents

This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals, as well as nove