4294-95-5

Basic information

• Product Name: 2-AMINO-4-METHOXY-BENZOIC ACID
• Synonyms: 2-AMINO-4-METHOXY-BENZOIC ACID;4-METHOXY-2-AMINO-BENZOIC ACID;4-METHOXYANTHRANILIC ACID;2-AMINO-4-METHOXYBENZOIC ACID ---OFF-WHITE POWDER, 99%---;2-amine-4-methoxybenzoic acid;2-azanyl-4-methoxy-benzoic acid;4-Methoxyanthranilic acid, 2-Carboxy-5-methoxyaniline, 3-Amino-4-carboxyanisole;4-METHOXY-2-AMINO-BENZOIC ACID(or 4-METHOXYANTHRANILIC ACID)
• CAS NO: 4294-95-5
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16
• Product Categories: pharmacetical
• Mol File: 4294-95-5.mol
• Article Data: 22

Chemical Properties

• Melting Point: 174-177°C
• Boiling Point: 339.8 °C at 760 mmHg
• Flash Point: 159.3 °C
• Appearance: /
• Density: 1.303 g/cm³
• Vapor Pressure: 3.47E-05mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 5.21±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4-METHOXY-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-METHOXY-BENZOIC ACID(4294-95-5)
• EPA Substance Registry System: 2-AMINO-4-METHOXY-BENZOIC ACID(4294-95-5)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39-37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 4294-95-5(Hazardous Substances Data)

Usage

Chemical Properties

Yellow powder

Uses

2-Amino-4-methoxybenzoic Acid, is an organic building block used in the synthesis of various chemical compounds.

InChI:InChI=1/C8H9NO3/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)

Upstream product

• 52351-75-4 6-methoxyisatin 
• 2836-00-2 3-amino-4-methylphenol 
• 33844-21-2 2-nitro-4-methoxybenzoic acid 
• 50868-78-5 2-acetamido-4-methoxybenzoic acid 
• 27191-09-9 m-anisidine hydrochloride 
• 6966-87-6 2-(hydroxyimino)-N-(3-methoxyphenyl)acetamide 
• 536-90-3 m-Anisidine 
• 38469-83-9 4-methoxy-2-nitro-benzonitrile 
• 96-96-8 4-methoxy-2-nitroaniline 
• 17484-36-5 4-Methyl-3-nitroanisole 
• 50868-75-2 5’-methoxy-2’-methylacetanilide 
• 621-42-1 meta-hydroxyacetanilide 
• 7440-05-3 palladium 
• 38487-91-1 2-amino-p-anisamide 

Downstream Products

• 2142-05-4 2-(3-methoxyphenyl)-1H-isoindole-1,3(2H)-dione 
• 16064-24-7 7-methoxyquinazoline-4(3H)-one 
• 861546-94-3 2-(carboxymethyl-amino)-4-methoxy-benzoic acid 
• 102879-57-2 4-methoxy-2-methylamino-benzoic acid 
• 19218-83-8 5-methoxydiphenylamine-2-carboxylic acid 
• 872279-05-5 2-(9,10-dioxo-9,10-dihydro-[1]anthrylamino)-4-methoxy-benzoic acid 
• 103203-39-0 2-[(carboxymethyl)thio]-4-methoxybenzoic acid 
• 21971-21-1 2-chloro-4-methoxybenzoic acid 
• 38918-51-3 7-methoxy-2-[4-methoxy-2-(toluene-4-sulfonylamino)-phenyl]-benzo[d][1,3]oxazin-4-one 
• 35673-26-8 7-methoxy-2-phenyl-4H-benzo[d][1,3]oxazin-4-one 
• 112239-02-8 4-Methoxy-2-(2-methoxycarbonyl-phenylamino)-benzoic acid 
• 117979-56-3 2-(2-acetyloxyphenyl)-7-methoxy-4H-3,1-benzoxazin-4-one 
• 766-85-8 3-methoxy-1-iodobenzene 
• 54435-09-5 2-iodo-4-methoxybenzoic acid 

Relevant articles and documents

Selenium-catalyzed intramolecular atom- And redox-economical transformation ofo-nitrotoluenes into anthranilic acids

Anthranilic acids (AAs) are significant basic chemicals used in pharmaceuticals, agrochemicals, dyes, fragrances,etc. Superfluous steps are always involved in obtaining AAs. Herein, we demonstrate a straightforward strategy to transform abundanto-nitrotoluenes into biologically and pharmaceutically significant AAs without any extra reductants, oxidants and protecting groups. Various sensitive groups, such as halogens, sulfide, aldehyde, pyridines, quinolines,etc., can be tolerated in this transformation. A hundred-gram-scale operation is realized efficiently with almost quantitative selenium recycling. Further mechanistic studies and DFT calculations disclosed the proposed atom-exchange processes and the key roles of the selenium species.

Antituberculosis Activity of the Antimalaria Cytochrome bcc Oxidase Inhibitor SCR0911

The ability to respire and generate adenosine triphosphate (ATP) is essential for the physiology, persistence, and pathogenicity of Mycobacterium tuberculosis, which causes tuberculosis. By employing a lead repurposing strategy, the malarial cytochrome bc

NOVEL ANTI-INFLAMMATORY AGENTS

Disclosed are methods of regulating interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides novel synthetic quinazolone compounds, as well as pharmaceutical compositions comprising those compounds.