50868-78-5Relevant articles and documents
Preparation method of Dactinib key intermediate
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Paragraph 0103-0107, (2021/04/28)
The invention provides a preparation method of a Dacomitinib key intermediate. The preparation method comprises the following steps: taking Dacomitinib as a raw material; the intermediate is short in synthetic route, mild in reaction condition, short in reaction time, simple in separation and purification method and low in cost, raw materials and reagents are all conventional reagents, and the prepared product is high in yield and quite beneficial to industrial production and popularization and has good application prospects.