1612-03-9

Basic information

• Product Name: (3-methylbut-1-yn-1-yl)benzene
• Synonyms: (3-Methylbut-1-yn-1-yl)benzene; 1-Phenyl-3-methyl-1-butyne; benzene, (3-methyl-1-butyn-1-yl)-; Benzene, (3-methyl-1-butynyl)-; Isopropyl-phenyl-acetylene
• CAS NO: 1612-03-9
• Molecular Formula: C₁₁H₁₂
• Molecular Weight: 144.213
• Mol File: 1612-03-9.mol
• Article Data: 38

Chemical Properties

• Boiling Point: 215.2°C at 760 mmHg
• Flash Point: 80.1°C
• Density: 0.92g/cm³
• Vapor Pressure: 0.219mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: (3-methylbut-1-yn-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (3-methylbut-1-yn-1-yl)benzene(1612-03-9)
• EPA Substance Registry System: (3-methylbut-1-yn-1-yl)benzene(1612-03-9)

Safety Data

• Hazardous Substances Data: 1612-03-9(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 628-71-7 1-Heptyne 
• 1776-66-5 triisopropylborane 
• 109431-70-1 4-phenylbut-3-yn-2-yl acetate 
• 3355-29-1 1,1-dimethyl-3-phenylprop-2-ynyl chloride 
• 33987-89-2 1-(isopropylsulfonyl)-2-phenylacetylene 
• 35460-31-2 (2-phenylsulfanylethynyl)benzene 
• 30615-19-1 isopropylmercury(II) chloride 
• 5324-64-1 2-(benzenesulfonyl)ethynylbenzene 
• 1719-19-3 2-Methyl-4-phenyl-3-butyn-2-ol 
• 58696-45-0 1,2-dichloro-3-methyl-1-phenyl-1-butene 
• 144108-81-6 (1,1-dibromo-3-methylbut-1-en-2-yl)benzene 
• 2307-69-9 toluene-4-sulfonic acid isopropyl ester 
• 27975-80-0 (+/-)-3-bromo-1-phenyl-1-butyne 

Downstream Products

• 6683-90-5 1,5-Di-isobutyl-1,5-dibenzylketazin 
• 56813-81-1 (E)-1-Bromo-3-methyl-1-phenyl-1-buten 
• 63318-12-7 ((E)-1-Chloro-2-iodo-3-methyl-but-1-enyl)-benzene 
• 58696-45-0 1,2-dichloro-3-methyl-1-phenyl-1-butene 
• 57787-14-1 1-Chlor-3-methyl-1-phenyl-1-buten 
• 61507-96-8 (E)-1-Chlor-3-methyl-1-phenyl-1-buten 
• 61507-97-9 (Z)-1-chloro-3-methyl-1-buten-1-ylbenzene 
• 1719-19-3 2-Methyl-4-phenyl-3-butyn-2-ol 
• 611-69-8 rac-2-methyl-1-phenylpropan-1-ol 
• 705-58-8 3-methyl-1-phenyl-2-butanol 
• 36004-04-3 ethyl (E)-1-phenylbut-1-en-3-ol 
• 103-05-9 4-phenyl-2-methyl-2-butanol 
• 57132-28-2 (E)-2-methyl-4-phenylbut-3-en-2-ol 
• 100-51-6 benzyl alcohol 

Relevant articles and documents

Enantioselective Three-Component Coupling of Heteroarenes, Cycloalkenes and Propargylic Acetates

Asymmetric coupling proceeds efficiently between propargylic acetates, cycloalkenes and electron-rich heteroarenes including indoles, pyrroles, activated furans and thiophenes. 2,3-Disubstituted tetrahydrofurans and pyrrolidines are produced in trans conf

Z-Selective Synthesis of α-Sulfanyl Carbonyl Compounds from Internal Alkynes and Thiols via Photoredox Catalysis

A synthetically useful Z-selective cascade formal thiyl radical addition, 1,3-double bond isomerization, oxygen trapping reaction, can be promoted by Eosin B under visible light, leading to the construction of 2-aryl- and alkylthio enone derivatives in good yields. An accurate study on the reactivity of different thiols and the screening of the reaction conditions, allowed us to extend this reaction to a large number of substrates, showing a good functional groups tolerance while highlighting the limitations of this procedure. Background experiments and mechanistic studies were also. performed to rationalize this cascade process. The usefulness of this methodology was finally demonstrated via the transformation of a series of α-sulfanyl-enone adducts through selected oxidation reactions, stereoselective synthesis of cyclopropyl ketones, indanones, and pyrazole compounds. (Figure presented.).

Nickel-Catalyzed Sonogashira Coupling Reactions of Nonactivated Alkyl Chlorides under Mild Conditions

The two nickel chlorides1and2with [P,S] and [P,Se] bidentate ligands, respectively, were synthesized and used as catalysts for Sonogashira coupling reaction. Both1and2are efficient catalysts for Sonogashira C(sp3)-C(sp) coupling reactions. Comp