611-69-8

Basic information

• Product Name: 2-METHYL-1-PHENYL-1-PROPANOL
• Synonyms: 1-Phenyl-2-methylpropyl alcohol;Benzenemethanol, alpha-(1-methylethyl)-;2-METHYL-1-PHENYL-1-PROPANOL;AURORA KA-6950;ISOPROPYL PHENYL CARBINOL;2-methyl-1-phenylpropan-1-ol;3-METHYL-1-PHENYL-1-PROPANOL, 98%;1-Phenyl-2-methyl-1-propanol
• CAS NO: 611-69-8
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.22
• EINECS: 210-274-5
• Mol File: 611-69-8.mol
• Article Data: 233

Chemical Properties

• Boiling Point: 124-125°C/15mm
• Flash Point: 124-125°C/15mm
• Appearance: /
• Density: 0.964
• Refractive Index: 1.5130
• Storage Temp.: 2-8°C
• PKA: 14.29±0.20(Predicted)
• Water Solubility: Not miscible or difficult to mix in water.
• CAS DataBase Reference: 2-METHYL-1-PHENYL-1-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-1-PHENYL-1-PROPANOL(611-69-8)
• EPA Substance Registry System: 2-METHYL-1-PHENYL-1-PROPANOL(611-69-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 611-69-8(Hazardous Substances Data)

Usage

Description

2-METHYL-1-PHENYL-1-PROPANOL, also known as 1-Phenyl-2-methylpropan-1-ol, is an organic compound with the molecular formula C10H14O. It is a colorless to pale yellow liquid with a distinctive aromatic odor. 2-METHYL-1-PHENYL-1-PROPANOL is characterized by its hydroxyl group and a phenyl ring attached to a three-carbon chain with a methyl group.

Uses

Used in Pharmaceutical Industry:
2-METHYL-1-PHENYL-1-PROPANOL is used as an intermediate in the large-scale preparation of (R)-and (S)-1-(2, 4, 6-triisopropylphenyl) ethanol, which are important chiral building blocks for the synthesis of various pharmaceutical compounds. Its application in this industry is due to its ability to provide a versatile starting material for the development of new drugs with potential therapeutic benefits.
Used in Flavor and Fragrance Industry:
2-METHYL-1-PHENYL-1-PROPANOL is used as a key component in the synthesis of various fragrances and flavor compounds. Its aromatic properties make it a valuable addition to the creation of scents and flavors for the perfume, cosmetics, and food industries.
Used in Chemical Synthesis:
2-METHYL-1-PHENYL-1-PROPANOL is utilized in the baker's yeast mediated asymmetric reduction of cinnamaldehyde derivatives. This process is significant in the production of chiral alcohols, which are essential in the synthesis of various chemicals, including pharmaceuticals, agrochemicals, and specialty chemicals. The use of this compound in this application is attributed to its ability to facilitate the selective reduction of cinnamaldehyde derivatives, leading to the formation of valuable chiral alcohols with high enantiomeric purity.

Synthesis Reference(s)

Tetrahedron, 50, p. 3447, 1994 DOI: 10.1016/S0040-4020(01)87024-1

InChI:InChI=1/C10H14O/c1-8(2)10(11)9-6-4-3-5-7-9/h3-8,10-11H,1-2H3

Upstream product

• 123-91-1 1,4-dioxane 
• 91-01-0 1,1-Diphenylmethanol 
• 556-91-2 aluminum tri-tert-butoxide 
• 611-70-1 phenyl isopropyl ketone 
• 1068-56-0 isopropylmagnesium iodide 
• 100-52-7 benzaldehyde 
• 920-39-8 isopropylmagnesium bromide 
• 78-84-2 isobutyraldehyde 
• 1612-03-9 3-methyl-1-phenyl-but-1-yne 
• 768-49-0 (2-methyl-1-propenyl)-benzene 
• 93-89-0 benzoic acid ethyl ester 
• 1068-55-9 isopropylmagnesium chloride 
• 83909-76-6 erythro-1-Phenyl-2-methyl-3-tosyloxy-propanol 
• 2973-10-6 diisopropyl sulfate 

Downstream Products

• 98656-16-7 (+/-)-phthalic acid mono-(2-methyl-1-phenyl-propyl ester) 
• 6668-27-5 2-methyl-1-phenyl-propylamine 
• 768-49-0 (2-methyl-1-propenyl)-benzene 
• 936-26-5 rac-1-chloro-2-methyl-1-phenylpropane 
• 57181-82-5 4-bromo-isobutylbenzene 
• 60295-99-0 carbamic acid-(2-methyl-1-phenyl-propyl ester) 
• 611-70-1 phenyl isopropyl ketone 
• 17659-34-6 1-Benzoyloxy-2-methyl-1-phenylpropane 
• 51310-27-1 N-(2-methyl-1-phenyl-propyl)-benzamide 
• 7653-94-3 1,1-dimethyl-2-phenylcyclopropane 
• 30836-86-3 1-benzyl-1-methylcyclopropane 
• 100-86-7 2-Methyl-1-phenyl-2-propanol 
• 64985-92-8 meso-2,5-dimethyl-3,4-diphenyl-hexane 
• 64985-92-8 racem.-2,5-dimethyl-3,4-diphenyl-hexane 

Relevant articles and documents

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