165117-54-4 Usage
Description
BrinzolaMide iMpurity, also known as (R)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Dioxide, is an impurity of Brinzolamide (AL-4862) [B677600], a topical carbonic anhydrase inhibitor.
Uses
Used in Pharmaceutical Industry:
BrinzolaMide iMpurity is used as an impurity in the development and manufacturing process of Brinzolamide, a carbonic anhydrase inhibitor. It is important to monitor and control the presence of this impurity to ensure the safety, efficacy, and quality of the final pharmaceutical product.
Check Digit Verification of cas no
The CAS Registry Mumber 165117-54-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,5,1,1 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 165117-54:
(8*1)+(7*6)+(6*5)+(5*1)+(4*1)+(3*7)+(2*5)+(1*4)=124
124 % 10 = 4
So 165117-54-4 is a valid CAS Registry Number.
165117-54-4Relevant articles and documents
Process for the preparation of (R)-(+)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide.
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Page/Page column 12-13, (2010/02/17)
Disclosed herein is an improved process for the preparation of (R)-(+)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide (Brinzolamide) and novel intermediates thereof.
Sulfonamides useful as carbonic anhydrase inhibitors
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, (2008/06/13)
Sulfonamides and pharmaceutical compositions containing the compounds useful in controlling intraocular pressure are disclosed. Methods for controlling intraocular pressure through administration of the compositions are also disclosed.
