1664-65-9

Basic information

• Product Name: Benzenepropanoic acid, 2-nitro-, methyl ester
• CAS NO: 1664-65-9
• Molecular Formula: C10H11NO4
• Molecular Weight: 209.202
• Mol File: 1664-65-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, 2-nitro-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, 2-nitro-, methyl ester(1664-65-9)
• EPA Substance Registry System: Benzenepropanoic acid, 2-nitro-, methyl ester(1664-65-9)

Safety Data

• Hazardous Substances Data: 1664-65-9(Hazardous Substances Data)

Upstream product

• 3958-60-9 2-nitrophenylmethyl bromide 
• 612-25-9 2-Nitrobenzyl alcohol 
• 859197-37-8 dimethyl 2-(2-nitrobenzyl)-malonate 
• 67-56-1 methanol 
• 1613-37-2 Quinoline N-oxide 
• 91-22-5 quinoline 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 771-19-7 1-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline 
• 577-19-5 2-nitrophenyl bromide 
• 39228-29-0 methyl 2-nitrocinnamate 
• 612-23-7 2-nitrobenzyl chloride 
• 114304-24-4 3-(2-nitrophenyl)propionitrile 
• 124-41-4 sodium methylate 
• 645-45-4 hydrocinnamic acid chloride 

Downstream Products

• 650629-21-3 3-(2-nitrophenyl)-2,2-dimethylpropionic acid methyl ester 
• 1493774-32-5 4-bromo-2-nitro-benzenepropanoic acid methyl ester 
• 1493774-03-0 C₁₀H₁₃NO₃ 
• 771-19-7 1-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline 
• 39228-29-0 (E)-methyl 2-nitrocinnamate 
• 2124-45-0 3-(2-Amino-phenyl)-propionsaeure-methylester 

Relevant articles and documents

NovelN-transfer reagent for converting α-amino acid derivatives to α-diazo compounds

A novel universalN-transfer reagent for direct and effective transformation of α-amino ketones, acetamides, and esters to the corresponding α-diazo products under mild basic conditions has been developed. This one-step synthetic approach not only allows for generation of α-substituted-α-diazo carbonyl compounds from α-amino acid derivatives but also permits preparation of α-diazo dipeptides fromN-terminal dipeptides (32 examples, up to 91%).

Reductive cyclizations of nitroarenes to hydroxamic acids by visible light photoredox catalysis

We have developed a photocatalytic reduction of nitroarenes as an efficient, chemoselective route to biologically important N-phenyl hydroxamic acid scaffolds. Optimal conditions call for 2.5 mol% of a ruthenium photocatalyst, visible light irradiation, and a dihydropyridine terminal reductant. Because of the mild nature of the visible light activation, functional groups that might be sensitive to other non-photochemical reduction methods are easily tolerated. Georg Thieme Verlag Stuttgart New York.

Suspension Ring-Opening Metathesis Polymerization: The Preparation of Norbornene-Based Resins for Application in Organic Synthesis

A series of norbornene-based resin beads were obtained by aqueous suspension ring-opening metathesis polymerization (ROMP) and used as polymeric supports for organic synthesis. These resins were prepared from norbornene, norborn-2-ene-5-methanol, and cross-linkers such as bis(norborn-2-ene-5-methoxy)alkanes, di(norborn-2-ene-5-methyl)ether, and 1,3-di(norborn-2-ene-5-methoxy)benzene. The resulting unsaturated ROMP (U-ROMP) resins containing olefin repeat units were chemically modified using hydrogenation, hydrofluorination, chlorination, and bromination reactions to produce saturated ROMP resins with different chemical and physical properties. The hydrogenated ROMP (H-ROMP) resin was found to be highly resistant to acidic, basic, Lewis acid, and Birch reduction conditions and was assessed as a polymeric support in a series of solid-phase synthetic applications. The H-ROMP resin was found to have superior performance compared to polystyrene-divinylbenzene (PS-DVB) copolymers in aromatic nitration and acylation reactions. In a conventional five-step solid-phase synthesis of a hydantoin, similar results were obtained for both the H-ROMP and PS-DVB resins. The U-ROMP resin was also shown to be effective in the solid-phase syntheses of benzimidazoles and benzimidazolones.