172940-57-7

Basic information

• Product Name: 2-bromo-N-methyl-N-phenylbenzylamine
• Synonyms: 2-bromo-N-methyl-N-phenylbenzylamine
• CAS NO: 172940-57-7
• Molecular Weight: 276.176
• Mol File: 172940-57-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-bromo-N-methyl-N-phenylbenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-methyl-N-phenylbenzylamine(172940-57-7)
• EPA Substance Registry System: 2-bromo-N-methyl-N-phenylbenzylamine(172940-57-7)

Safety Data

• Hazardous Substances Data: 172940-57-7(Hazardous Substances Data)

Upstream product

• 100-61-8 N-methylaniline 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 30319-92-7 5-methyl-5,6-dihydro-phenanthridine 
• 614-30-2 N-methyl-N-phenyl-benzenemethanamine 
• 157330-05-7 Na⁽¹⁺⁾*(OH)2B(C₆H₄)CH₂N(CH₃)C₆H₄N₂(C₆H₄)SO₃^(1-) = Na((OH)2B(C₆H₄)CH₂N(CH₃)C₆H₄N₂(C₆H₄)SO₃) 
• 172940-58-8 (2-([methyl(phenyl)amino]methyl)phenyl)boronic acid 

Relevant articles and documents

Microwave assisted synthesis of phenanthridinones and dihydrophenanthridines by vasicine/KO: T Bu promoted intramolecular C-H arylation

A simple, efficient, rapid and transition metal-free methodology has been developed by utilizing vasicine (a natural product), as a catalyst for the synthesis of phenanthridinones and dihydrophenanthridines. The reaction proceeds through intramolecular C-H arylation with aryl halides in the presence of KOtBu as a base under microwave irradiation in sulfolane as a solvent. The reaction proceeds well with various aryl iodides, bromides and more remarkably with less reactive aryl chlorides for 15 minutes, providing the corresponding products in 45-90% yields.

Regioselective, Photocatalytic α-Functionalization of Amines

Photocatalytic α-functionalization of amines provides a mild and atom-economical means to synthesize α-branched amines. Prior examples featured symmetrical or electronically biased substrates. Here we report a controllable α-functionalization of amines in which regioselectivity can be tuned with minor changes to the reaction conditions.

General Reductive Amination of Aldehydes and Ketones with Amines and Nitroaromatics under H2 by Recyclable Iridium Catalysts

Heterogeneous iridium catalysts were prepared and applied for the reductive amination of aldehydes and ketones with nitroaromatics and amines using H2. The iridium catalysts were prepared by pyrolysis of ionic liquid 1-methyl-3-cyanomethylimidazoulium chloride ([MCNI]Cl) with iridium chloride (IrCl3) in activated carbons. Iridium particles were well dispersed and stable in the N-doped carbon materials from [MCNI]Cl with activated carbon. The Ir@NC(600-2h) catalyst was found to be highly active and selective for the reductive amination of aldehydes and ketones using H2 and a variety of nitrobenzenes and amines were selectively converted into the corresponding secondary and tertiary amines. The Ir@NC(600-2h) catalyst can be reusable several times without evident deactivation.