173051-70-2Relevant articles and documents
Design and evaluation of nonpeptide fibrinogen γ-chain based GPIIb/IIIa antagonists
Hoekstra,Beavers,Andrade-Gordon,Evangelisto,Keane,Press,Tomko,Fan,Kloczewiak,Mayo,Durkin,Liotta
, p. 1582 - 1592 (2007/10/02)
Two series of nonpeptide turn mimetics were designed by analysis of the solution NMR structure of the 385-411 sequence of the γ-chain of fibrinogen. These compounds, based on the KQAGD (Lys-Gln-Ala-Gly-Asp, 406-410) sequence, were synthesized and studied