89895-55-6

Basic information

• Product Name: METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE
• Synonyms: METHYL NIPECOTATE HYDROCHLORIDE;METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE;Methylpiperidine-3-carboxylate,HCl;3-Piperidinecarboxylicacid, Methyl ester, hydrochloride (1:1);Piperidine-3-carboxylic acid methyl ester hydrochloride;3-Piperidinecarboxylic acid methyl ester hydrochloride;RS-3-Piperidinecarboxylic acid methyl ester hydrochloride
• CAS NO: 89895-55-6
• Molecular Formula: C₇H₁₃NO₂*ClH
• Molecular Weight: 179.64
• EINECS: 203-126-8
• Mol File: 89895-55-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 235.3 °C at 760 mmHg
• Flash Point: 96.1 °C
• Appearance: /
• Vapor Pressure: 0.0408mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE(89895-55-6)
• EPA Substance Registry System: METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE(89895-55-6)

Safety Data

• Hazardous Substances Data: 89895-55-6(Hazardous Substances Data)

Usage

Uses

Methyl Piperidine-3-carboxylate Hydrochloride is used in preparation of indazole carboxamides as RIPK1 kinase inhibitors.

InChI:InChI=1/C7H13NO2.ClH/c1-10-7(9)6-3-2-4-8-5-6;/h6,8H,2-5H2,1H3;1H

Upstream product

• 67-56-1 methanol 
• 498-95-3 nipecotic acid 
• 6034-80-6 piperidine-3-carboxylic acid hydrochloride 
• 59-67-6 nicotinic acid 

Downstream Products

• 148763-41-1 1-(tert-butyl) 3-methyl piperidine-1,3-dicarboxylate 
• 111479-16-4 N-acetyl-piperidine-3-carboxylic acid methyl ester 
• 164224-90-2 3-{[1-(3-Pyridin-4-yl-propionyl)-piperidine-3-carbonyl]-amino}-propionic acid benzyl ester 
• 173051-70-2 <<<1-(6-Boc-aminocaproyl)piperid-3-yl>methyl>amino>propionic acid benzyl ester 
• 173051-63-3 3-{[1-(6-tert-Butoxycarbonylamino-hexanoyl)-piperidine-3-carbonyl]-amino}-propionic acid benzyl ester 
• 1053590-19-4 C₄₃H₅₄N₆O₁₀ 
• 173299-58-6 N^α-Boc-L-Lys(Cbz)-Nip-β-Ala-OBn 
• 209403-25-8 3-{[1-((R)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoyl)-piperidine-3-carbonyl]-amino}-propionic acid benzyl ester 

Relevant articles and documents

SUBSTITUTED (PIPERIDIN-1-YL)ARYL ANALOGUES FOR MODULATING AVILACTIVITY

In one aspect, the disclosure relates to compounds useful to regulate, limit, or inhibit the expression of AVIL (advillin), methods of making same, pharmaceutical compositions comprising same, and methods of treating disorders associated with AVIL dysregulation using same. In aspects, the disclosed compounds, compositions and methods are useful for treating disorders or diseases in which the regulation, limitation, or inhibition of the expression of AVIL can be clinically useful, such as, for example, the treatment of cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Chemoenzymatic approach to enantiopure piperidine-based β-amino esters in organic solvents

This research concentrates on the enantioselectivities of lipase-catalysed reactions with methyl esters of 2-piperidylacetic acid and 3-piperidinecarboxylic acid derivatives. N-Acetylated 2-piperidylacetic acid methyl ester displayed good enantioselectivi