176713-85-2

Basic information

• Product Name: [(2-Chloro-phenyl)-phenyl-methyl]-phosphonic acid diethyl ester
• CAS NO: 176713-85-2
• Molecular Weight: 338.771
• Mol File: 176713-85-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(2-Chloro-phenyl)-phenyl-methyl]-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(2-Chloro-phenyl)-phenyl-methyl]-phosphonic acid diethyl ester(176713-85-2)
• EPA Substance Registry System: [(2-Chloro-phenyl)-phenyl-methyl]-phosphonic acid diethyl ester(176713-85-2)

Safety Data

• Hazardous Substances Data: 176713-85-2(Hazardous Substances Data)

Upstream product

• 6954-45-6 (2-chlorophenyl)(phenyl)methanol 
• 5162-03-8 (2-chlorophenyl)(phenyl)methanone 
• 75341-34-3 (2-chlorophenyl)phenylbromomethane 
• 122-52-1 triethyl phosphite 

Relevant articles and documents

Benzylphosphonic acid inhibitors of human prostatic acid phosphatase

A series of α-substituted benzylphosphonic acids is described as inhibitors of human prostatic acid phosphatase, an enzyme has been used as a model to study aryl phosphatases. The most potent inhibitors in this series are 2-trifluoromethylbenzhydrylphosphonic acid (9 μM), and α-(2-phenylethyl)benzylphosphonic acid (14 μM). The structure-activity studies suggest that bulk tolerance beyond the phosphate binding area limits the steric or hydrophobic contribution to inhibitor potency achieved through α-carbon substitution.