75341-34-3

Basic information

• Product Name: (2-chlorophenyl)phenylbromomethane
• Synonyms: (2-chlorophenyl)phenylbromomethane
• CAS NO: 75341-34-3
• Molecular Weight: 281.579
• Mol File: 75341-34-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2-chlorophenyl)phenylbromomethane(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chlorophenyl)phenylbromomethane(75341-34-3)
• EPA Substance Registry System: (2-chlorophenyl)phenylbromomethane(75341-34-3)

Safety Data

• Hazardous Substances Data: 75341-34-3(Hazardous Substances Data)

Upstream product

• 5162-03-8 (2-chlorophenyl)(phenyl)methanone 
• 6954-45-6 (2-chlorophenyl)(phenyl)methanol 

Downstream Products

• 205389-75-9 [(2-(2-Chlorophenyl)(phenyl)methylsulfonyl-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy]acetic Acid 
• 176713-85-2 [(2-Chloro-phenyl)-phenyl-methyl]-phosphonic acid diethyl ester 

Relevant articles and documents

Synthesis and anticonvulsant activity of some cinnamylpiperazine derivatives

A series of cinnamylpiperazine derivatives was synthesized using different benzophenone as starting material. The structures of the compounds were proved by their IR, 1H-NMR spectroscopic data and mass spectra data. The anticonvulsant activities of these compounds were evaluated with maximal electroshock (MES) test and rotarod test with intraperitoneal injection on KunMing mice. Among all the flunarizine analogues, no one exhibited better anticonvulsant activity than flunarizine. Flunarizine (4i) exhibited anticonvulsant activity with ED50 of 38.1 mg/kg, TD50 of 164.3 mg/kg and PI of 4.3 through administration intraperitoneal, and with ED50 of 56.8 mg/kg, TD50 of 456.3 mg/kg and PI of 8.0 through oral administration.

Tricyclic compounds, their production and use

A compound of the formula: wherein R1 is H or a substituent; m is 1-3; Ar is an aromatic group which may be substituted; X is a bond or a divalent straight-chain group having 1-6 atoms which may be substituted; Y is —S—, —O—, or —N(R2— (R2 is H or a substituent group), Z is —N= or —C(R3)= (R3 is H or a hydrocarbon group), ring A is a benzene ring; ring B is a 5- to 7-membered ring which may be substituted, or a salt thereof is useful for eliciting a prostaglandin I2 receptor agonistic effect.