17745-40-3

Basic information

• Product Name: Benzoic acid, 4-(1-oxopropyl)-, methyl ester
• CAS NO: 17745-40-3
• Molecular Formula: C11H12O3
• Molecular Weight: 192.214
• Mol File: 17745-40-3.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(1-oxopropyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(1-oxopropyl)-, methyl ester(17745-40-3)
• EPA Substance Registry System: Benzoic acid, 4-(1-oxopropyl)-, methyl ester(17745-40-3)

Safety Data

• Hazardous Substances Data: 17745-40-3(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 4219-55-0 4-propionylbenzoic acid 
• 201230-82-2 carbon monoxide 
• 619-44-3 methyl 4-iodobenzoate 
• 96-10-6 diethylaluminium chloride 
• 245679-66-7 N-cyclohexyl-4-(methoxycarbonyl)benzamide 
• 925-90-6 ethylmagnesium bromide 
• 811-49-4 ethyllithium 
• 923-34-2 Triethylindium 
• 135738-30-6 ethylcerium dichloride 
• 74-85-1 ethene 
• 1679-64-7 Monomethyl terephthalate 
• 97-94-9 triethyl borane 
• 3609-53-8 methyl 4-acetylbenzoate 

Downstream Products

• 58764-22-0 methyl 4-(2-bromopropanoyl)benzoate 
• 33036-62-3 4-Bromo-1-butanol 
• 81631-63-2 p-(methoxycarbonyl)-n-propylbenzene 
• 1196046-98-6 methyl 4-(1-aminopropyl)benzoate hydrochloride 
• 1186680-40-9 4-((E)-1-benzyloxycarbonylmethylpropenyl)benzoic acid methyl ester 
• 142721-21-9 Methyl 4-[[2-(2,4-Diamino-5-methylpyrido[2,3-d]-pyrimidin-6-yl)-1-ethyl]ethenyl]benzoate 
• 142721-20-8 methyl 4-<2-(2,4-diamino-6-pteridinyl)-1-ethylethenyl>benzoate 

Relevant articles and documents

Photoredox/nickel-catalyzed hydroacylation of ethylene with aromatic acids

We report a general, practical and scalable hydroacylation reaction of ethylene with aromatic carboxylic acids with the synergistic combination of nickel and photoredox catalysis. Under ambient temperature and pressure, feedstock chemicals such as ethylene can be converted into high-value-added aromatic ketones in moderate to good yields (up to 92%) with reaction time of 2-6 hours.

DMF as carbon source: Rh-catalyzed α-methylation of ketones

An unprecedented Rh-catalyzed direct methylation of ketones with N,N-dimethylformamide (DMF) is disclosed. The reaction shows a broad substrate scope, tolerating both aryl and alkyl ketones with various substituents. Mechanistic studies suggest that DMF delivers a methylene fragment followed by a hydride in the methylation process.

Efficient synthesis of alkyl aryl ketones & ketals via palladium-catalyzed regioselective arylation of vinyl ethers

The combination of Pd(OAc)2 with 1,3-bis(diphenylphosphino) propane (dppp) in ethylene glycol constitutes a high-performance catalytic system for highly regioselective arylation of a range of electron-rich vinyl ethers by aryl bromides to provide, upon hydrolysis, alkyl aryl ketones and cyclic ketals in good yields with up to 3.75 × 105 TON and 15625 h-1 TOF.