177485-39-1

Basic information

• Product Name: ethyl imidazo[1,2-a]pyridine-5-carboxylate
• Synonyms: ethyl imidazo[1,2-a]pyridine-5-carboxylate;IMidazo[1,2-a]pyridine-5-carboxylicacid,ethylester
• CAS NO: 177485-39-1
• Molecular Formula: C10H10N2O2
• Molecular Weight: 190.201
• Mol File: 177485-39-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.228 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.73±0.50(Predicted)
• CAS DataBase Reference: ethyl imidazo[1,2-a]pyridine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl imidazo[1,2-a]pyridine-5-carboxylate(177485-39-1)
• EPA Substance Registry System: ethyl imidazo[1,2-a]pyridine-5-carboxylate(177485-39-1)

Safety Data

• Hazardous Substances Data: 177485-39-1(Hazardous Substances Data)

Usage

General Description

Ethyl imidazo[1,2-a]pyridine-5-carboxylate is a chemical compound with the molecular formula C11H10N2O2. It is a member of the imidazo[1,2-a]pyridine class of compounds and is characterized by its imidazole and pyridine rings. Ethyl imidazo[1,2-a]pyridine-5-carboxylate is commonly used in organic synthesis and medicinal chemistry, specifically in the development of pharmaceuticals and bioactive molecules. Its unique structure and properties make it a valuable building block for creating new drugs and chemical entities. Additionally, ethyl imidazo[1,2-a]pyridine-5-carboxylate may have potential biological activities that make it of interest for further research and development in the field of pharmacology.

Upstream product

• 107-20-0 2-chloroethanal 
• 69142-64-9 ethyl 6-aminopicolinate 

Downstream Products

• 372147-50-7 imidazo[1,2-a]pyridine-5-carbaldehyde 
• 167884-17-5 5-hydroxymethylimidazo[1,2-a]pyridine 
• 429690-42-6 ethyl 3-bromoimidazo[1,2-a]pyridine-5-carboxylate 
• 429690-43-7 3-bromoimidazo[1,2-a]pyridine-5-carbaldehyde 
• 429690-44-8 3-nitroimidazo[1,2-a]pyridine-5-carbaldehyde 
• 372147-66-5 (Z)-ethyl α-[(triphenylphosphoranylidene)amino]-β-(imidazo[1,2-a]pyridin-5-yl)propenoate 

Relevant articles and documents

BENZISOXAZOLE COMPOUND

Disclosed is a compound represented by the general formula (I) or a salt thereof: wherein any one of R1, R2 and R3 represents a group represented by the formula: -(CH2)m-NR11R12 (wherein m is 1 or 2; and R11 and R12 independently represent a hydrogen atom or a C1-6 alkyl group or may, together with a nitrogen atom to which R11 and R12 are bound, form a 4- or 5-membered cyclic group); the remaining two or R1, R2 and R3 independently represent a group represented by the formula: -(O)n-R21 (wherein n is 0 or 1; and R21 represents a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, or the like); and R4 represents a C1-6 alkyl group which may have a substituent or the like.

Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-α]pyridines

Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-α]pyridines was explored experimentally and theoretically using semiempirical AM1 and ab initio methods. A range of functionalized vinylic derivatives (azido, amino, and carbodiimide groups) were prepared for conversion into pyrroloazaindoles 19-22, imidazo[1,x]-; (x=5, 6, 7, 8), [2,6]-, and [2,7]naphthyridines 28-30, 35-38 by thermal reaction. In the case of vinylic groups in the 5 position, peri annulation also was observed. The experimental and theoretical data are compared and discussed.