17857-14-6

Basic information

• Product Name: (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
• Synonyms: (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE;3-Carboxypropyltriphenylphosphonium bromide 98+%;3-Carboxypropyl triphenylphosphonium bromide,97%;PhosphoniuM,(3-carboxypropyl)triphenyl-, broMide (1:1);3-Carboxypropyltriphenylphosph;(3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide 98+%;(3-Carboxypropyl)triphenylphosphoniuM broMide 98%;(4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide
• CAS NO: 17857-14-6
• Molecular Formula: Br*C₂₂H₂₂O₂P
• Molecular Weight: 429.29
• EINECS: -0
• Product Categories: Miscellaneous Compounds;Phosphonium Compounds;C-C Bond Formation;Olefination;Wittig Reagents;Indolines ,Indoles ,Indazoles
• Mol File: 17857-14-6.mol
• Article Data: 32

Chemical Properties

• Melting Point: 244-247 °C(lit.)
• Appearance: White/Crystalline Powder, Crystals, or Flakes
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility: Soluble in water. soluble in ethanol.
• Sensitive: Hygroscopic
• BRN: 4173599
• CAS DataBase Reference: (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE(17857-14-6)
• EPA Substance Registry System: (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE(17857-14-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 17857-14-6(Hazardous Substances Data)

Usage

Description

(3-Carboxypropyl)triphenylphosphonium bromide is a white powder and granules that is a reagent used in various chemical reactions and has potential applications in pharmaceutical and medical fields.

Uses

Used in Suzuki Reaction:
(3-Carboxypropyl)triphenylphosphonium bromide is used as a reagent in the Suzuki reaction, a type of cross-coupling reaction in organic chemistry.
Used in Pharmaceutical Industry:
(3-Carboxypropyl)triphenylphosphonium bromide is used as antimalarial agents, antimycobacterial agents, and antifungal agents for their potential therapeutic effects against various diseases.
Used in Enzyme Inhibition:
(3-Carboxypropyl)triphenylphosphonium bromide is used as inhibitors of protein tyrosine phosphatase, which play a role in regulating cellular processes.
Used in Drug Development:
(3-Carboxypropyl)triphenylphosphonium bromide is used in the preparation of sphingosine 1-phosphate-1 receptor antagonists, which have potential applications in treating various diseases.
Used in Mitochondrial Function Studies:
(3-Carboxypropyl)triphenylphosphonium bromide is used in the synthesis of mitochondrial vitamin E metabolites and other mitochondrial targets, which can help in understanding mitochondrial functions and their role in diseases.
Used in Cancer Research:
(3-Carboxypropyl)triphenylphosphonium bromide is used in the preparation of benzosuberene analogs that inhibit tubulin assembly and demonstrate cytotoxicity, which can be useful in developing new cancer therapies.

InChI:InChI=1/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H

Upstream product

• 96-48-0 4-butanolide 
• 6399-81-1 triphenylphosphine hydrobromide 
• 2623-87-2 bromobutyric acid 
• 603-35-0 triphenylphosphine 

Downstream Products

• 791-28-6 Triphenylphosphine oxide 
• 50479-11-3 (3-ethoxycarbonylpropyl)triphenylphosphonium bromide 
• 146072-53-9 5-cyclopropyl-5-phenylbut-4-enoic acid 
• 146072-52-8 5-cyclopropyl-5-phenylbut-4-enoic acid 
• 105284-21-7 butanoic acid, 4-[(1S,2S,3R,6S)-2-[(3S)-3-cyclohexyl-3-hydroxy-1-propynyl]-3-hydroxybicyclo[4.2.0]oct-7-ylidene]-(4Z) 
• 105880-50-0 4-[(1S,2S,3R,6S)-2-((S)-3-Cyclohexyl-3-hydroxy-prop-1-ynyl)-3-hydroxy-bicyclo[4.2.0]oct-(7E)-ylidene]-butyric acid 
• 23518-25-4 (+/-)-prostaglandin-F₂α 
• 551-11-1 rac-15-epi-PGF_2α 
• 118908-08-0 15-(t-butyldiphenylsilyl) PGF_2α 
• 105880-66-8 RS₉₃₅₂₀ 
• 153732-04-8 (E)-5-[4-(2-{[(4-chlorophenyl)sulfonyl]amino}ethyl)phenyl]-5-(3-pyridyl)pent-4-enoic acid 

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