1835-04-7

Basic information

• Product Name: 1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE
• Synonyms: 3',4'-DIMETHOXY-1-PHENYLPROPIOPHENONE;3,4-DIMETHOXYPROPIOPHENONE;1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE;Ethyl 3,4-dimethoxyphenyl ketone;NSC 16954;Propioveratrone
• CAS NO: 1835-04-7
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Product Categories: Aromatic Propiophenones (substituted);Aromatics
• Mol File: 1835-04-7.mol
• Article Data: 39

Chemical Properties

• Melting Point: 62–63°C
• Boiling Point: 270.67°C (rough estimate)
• Flash Point: 123.2 ºC
• Appearance: /
• Density: 1.1224 (rough estimate)
• Vapor Pressure: 0.00154mmHg at 25°C
• Refractive Index: 1.4600 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, Dichloromethane, Ether, Ethyl Acetate, Methanol
• CAS DataBase Reference: 1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE(1835-04-7)
• EPA Substance Registry System: 1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE(1835-04-7)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 1835-04-7(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Semi-Solid

Uses

3,4-Dimethoxypropiophenone (cas# 1835-04-7) is a compound useful in organic synthesis.

Preparation

Preparation by reaction of dimethyl sulfate with propionylcatechol in alkaline solution (43%).

InChI:InChI=1/C11H14O3/c1-4-9(12)8-5-6-10(13-2)11(7-8)14-3/h5-7H,4H2,1-3H3

Upstream product

• 1208-70-4 4-(1,2-dibromo-propyl)-1,2-dimethoxy-benzene 
• 1568-01-0 3-(N,N-dimethylamino)-1-(3,4-dimethoxyphenyl)propan-1-one 
• 70946-18-8 N,N-diethyl-3,4-dimethoxybenzamide 
• 925-90-6 ethylmagnesium bromide 
• 91-16-7 1,2-dimethoxybenzene 
• 79-03-8 propionyl chloride 
• 802294-64-0 propionic acid 
• 123-62-6 propionic acid anhydride 
• 7451-98-1 3',4'-dihydroxypropiophenone 
• 77-78-1 dimethyl sulfate 
• 1835-09-2 1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1-propanone 
• 10548-83-1 1-(3,4-dimethoxyphenyl)propan-1-ol 
• 6379-72-2 1,2-dimethoxy-4-(E)-propenylbenzene 
• 126065-87-0 1,2-dimethoxy-4-(prop-1-yn-1-yl)benzene 

Downstream Products

• 108845-25-6 (E)-4-(but-2-en-2-yl)-1,2-dimethoxybenzene 
• 103502-07-4 1-(3,4-dimethoxy-phenyl)-propane-1,2-dione-2-oxime 
• 101589-21-3 1-(3,4-dimethoxy-phenyl)-propylamine 
• 1835-05-8 2-bromo-1-(3,4-dimethoxyphenyl)propan-1-one 
• 10548-83-1 1-(3,4-dimethoxyphenyl)propan-1-ol 
• 5888-52-8 4-propyl-1,2-dimethoxybenzene 
• 91134-62-2 1-(4,5-dimethoxy-2-nitrophenyl)-1-propanone 
• 105906-60-3 1-(3,4-dimethoxy-phenyl)-propan-1-one semicarbazone 
• 18885-56-8 1-ethylidene-3-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2-methyl-indene 
• 15547-70-3 3-(3,4-dimethoxy-phenyl)-pent-2-enoic acid ethyl ester 
• 4440-92-0 1,4-bis(3,4-dimethoxyphenyl),2,3-dimethylbutane-1,4-dione 
• 4302-34-5 β-Chlor-α-methyl-3,4-dimethoxy-zimtaldehyd 
• 85720-34-9 cis-3,4-bis(3,4-dimethoxyphenyl)hex-3-ene 
• 75513-68-7 3,4-bis-(3',4'-dimethoxyphenyl)-hex-3-ene 

Relevant articles and documents

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Cleavage of CC and Co bonds in β-O-4 linkage of lignin model compound by cyclopentadienone group 8 and 9 metal complexes

Degradation of 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphe-noxy)propane-1,3-diol (1), a model compound for lignin β-O-4 linkage was examined with iron, ruthenium, rhodium and iridium complexes bearing cyclopentadienone ligand. Cyclopentadienone iron complex gave only a small amount of degraded product with reduced molecular weight. Cyclopentadienone ruthenium complex, so called Shvo's catalyst, afforded 3,4-dimethoxybenzaldehyde (a3) in 14.3% yield after CαCβ bond cleavage. On the other hand, cyclopentadienone group-9 metal complexes catalyzed CβO bond cleavage to afford guaiacol (b1) as a main product in up to 74.9% yield.

Preparation method and application of apocynin and derivatives of apocynin

The invention belongs to the technical field of chemical biology, and particularly relates to a preparation method of apocynin and derivatives of the apocynin and an application of the apocynin and the derivatives of the apocynin in skin care products. The apocynin and the derivatives of the apocynin provided by the invention can promote collagen synthesis, help skin damage repair, and can be usedin the skin care products.

METHOD FOR THE DEACYLATION AND/OR DEALKYLATION OF COMPOUNDS

The present invention in general relates to a method for the deacylation and/or dealkylation (both O-dealkylation as well as C-dealkylation) of compounds, more specifically of aromatic compounds. The method is characterized by contacting the compound with an acid-containing aqueous reaction mixture using high temperature and high pressure conditions. The invention also provides a method for preparing a compound suitable for further deacylation using the method of the invention.