18546-37-7 Usage
Description
2-Deoxy-L-ribose is a white to light beige crystalline powder and an isomer of 2-Deoxy-D-ribose (D252000). It plays a significant role in cellular processes by inducing apoptosis through the inhibition of glutathione synthesis and increasing its efflux.
Uses
Used in Pharmaceutical Industry:
2-Deoxy-L-ribose is used as a pharmaceutical compound for its ability to induce apoptosis in cells. This property makes it a potential candidate for the development of treatments targeting various diseases, particularly those involving abnormal cell growth or cancer.
Used in Research Applications:
In the field of research, 2-Deoxy-L-ribose is utilized as a biochemical tool to study the effects of apoptosis and glutathione metabolism. Its unique properties allow scientists to gain insights into cellular processes and develop new therapeutic strategies.
Used in Drug Development:
2-Deoxy-L-ribose is used as a key component in the development of new drugs that target apoptosis and glutathione metabolism. Its potential application in cancer treatment and other therapeutic areas makes it a valuable compound for pharmaceutical research and development.
Used in Biochemical Analysis:
As a crystalline powder, 2-Deoxy-L-ribose is also used in biochemical analysis to study the structure and function of various biomolecules. Its isomer properties provide a basis for comparative studies and contribute to the understanding of molecular interactions in biological systems.
Purification Methods
Crystallise 2-deoxy--L-ribose from diethyl ether. It can also be purified by dissolving the ribose (7.3g) in EtOAc (3L) by reflux, decanting from any insoluble mate
Check Digit Verification of cas no
The CAS Registry Mumber 18546-37-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,5,4 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18546-37:
(7*1)+(6*8)+(5*5)+(4*4)+(3*6)+(2*3)+(1*7)=127
127 % 10 = 7
So 18546-37-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m1/s1
18546-37-7Relevant articles and documents
Production method of 2-deoxy-L-ribose compound
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Page/Page column 15, (2010/02/13)
An aldehyde compound represented by the formula (1) is reacted with an organometallic compound represented by the formula (2) to give an alcohol compound represented by the formula (3), which is then subjected to deprotection of a hydroxyl group and production of aldehyde by acid hydrolysis. wherein R1 and R2 are each independently a hydroxyl-protecting group or R1 and R2 in combination show a hydroxyl-protecting group, R3 and R4 are each independently an alkyl group, an aralkyl group, an aryl group or a silyl group or R3 and R4 in combination show a cyclic alkyl group.
