185525-70-6

Basic information

• Product Name: Carbamic acid, [3-cyclohexyl-1-[(2,3-dihydrospiro[1H-indene-1,4'-piperidin]-1'-yl)carbon yl]propyl]-, 1,1-dimethylethyl ester, (R)-
• CAS NO: 185525-70-6
• Molecular Formula: C28H42N2O3
• Molecular Weight: 454.653
• Mol File: 185525-70-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [3-cyclohexyl-1-[(2,3-dihydrospiro[1H-indene-1,4'-piperidin]-1'-yl)carbon yl]propyl]-, 1,1-dimethylethyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [3-cyclohexyl-1-[(2,3-dihydrospiro[1H-indene-1,4'-piperidin]-1'-yl)carbon yl]propyl]-, 1,1-dimethylethyl ester, (R)-(185525-70-6)
• EPA Substance Registry System: Carbamic acid, [3-cyclohexyl-1-[(2,3-dihydrospiro[1H-indene-1,4'-piperidin]-1'-yl)carbon yl]propyl]-, 1,1-dimethylethyl ester, (R)-(185525-70-6)

Safety Data

• Hazardous Substances Data: 185525-70-6(Hazardous Substances Data)

Upstream product

• 148835-99-8 N-Boc spiroindane 
• 428-38-6 2,3-dihydrospiro[1H-indene-1,4'-piperidine] 
• 154731-88-1 2-tert-butoxycarbonylamino-4-cyclohexyl-butyric acid 

Relevant articles and documents

Synthesis and biological activities of spiroheterocyclic growth hormone secretagogues

The synthesis and biological activities of a series of spiroheterocyclic growth hormone secretagogues are reported. Modification of the spiroindane part-structure of the prototypal secretagogue L-162,752 revealed that the spiroindane could be replaced with spirobenzodihydrothiophen derivatives to enhance not only in vitro potency but also oral activity. In this study non- aromatic D-2-amino-4-cyclohexylbutanoic analogs (8a-8d) were also identified to be active secretagogues.