188198-38-1 Usage
General Description
2H-1-Benzopyran-4-amine, 3,4-dihydro-, (4S)-(9CI) is a chemical compound with a molecular formula C9H11NO. It is also known by the names 3,4-dihydro-4-aminocoumarin and (S)-5,6-Dihydro-4H-1-benzopyran-4-amine. 2H-1-Benzopyran-4-amine,3,4-dihydro-,(4S)-(9CI) is a heterocyclic amine that belongs to the benzopyrans class. It is a synthetic derivative of coumarins, a group of natural compounds found in various plants. The compound has been studied for its potential pharmacological activities, including its potential antiproliferative, anti-inflammatory, and anticoagulant effects. Its chemical structure and properties make it a subject of interest in medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 188198-38-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,1,9 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 188198-38:
(8*1)+(7*8)+(6*8)+(5*1)+(4*9)+(3*8)+(2*3)+(1*8)=191
191 % 10 = 1
So 188198-38-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-4,8H,5-6,10H2/t8-/m0/s1
188198-38-1Relevant articles and documents
Kinetic Resolution of Racemic Primary Amines Using Geobacillus stearothermophilus Amine Dehydrogenase Variant
Tseliou, Vasilis,Knaus, Tanja,Vilím, Jan,Masman, Marcelo F.,Mutti, Francesco G.
, p. 2184 - 2188 (2020/03/11)
A NADH-dependent engineered amine dehydrogenase from Geobacillus stearothermophilus (LE-AmDH-v1) was applied together with a NADH-oxidase from Streptococcus mutans (NOx) for the kinetic resolution of pharmaceutically relevant racemic α-chiral primary amines. The reaction conditions (e. g., pH, temperature, type of buffer) were optimised to yield S-configured amines with up to >99 % ee.
Catalytic enantioselective borane reduction of benzyl oximes: Preparation of (S)-1-pyridin-3-YL-ethylamine bis hydrochloride
Huang, Kun,Ortiz-Marciales, Margarita,Hughes, David
scheme or table, p. 36 - 52 (2011/05/13)
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Catalytic asymmetric hydroboration-amination
Fernandez, Elena,Hooper, Mark W.,Knight, Frances I.,Brown, John M.
, p. 173 - 174 (2007/10/03)
A one-pot asymmetric synthesis of primary amines from vinylarenes via catalytic hydroboration is described.