18859-35-3

Basic information

• Product Name: 1-(4-CHLOROPHENOXY)-2-PROPANONE
• Synonyms: 1-(4-CHLOROPHENOXY)-2-PROPANONE;1-(4-chlorophenoxy)acetone
• CAS NO: 18859-35-3
• Molecular Formula: C₉H₉ClO₂
• Molecular Weight: 184.62
• Mol File: 18859-35-3.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 268.1 °C at 760 mmHg
• Flash Point: 114.2 °C
• Appearance: /
• Density: 1.187 g/cm³
• Vapor Pressure: 0.00782mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: 1-(4-CHLOROPHENOXY)-2-PROPANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-CHLOROPHENOXY)-2-PROPANONE(18859-35-3)
• EPA Substance Registry System: 1-(4-CHLOROPHENOXY)-2-PROPANONE(18859-35-3)

Safety Data

• Hazardous Substances Data: 18859-35-3(Hazardous Substances Data)

Usage

General Description

1-(4-chlorophenoxy)-2-propanone, also known as 4-Chlorophenyl 2-propanone, is a chemical compound with the formula C9H9ClO2. It is a pale yellow to light brown liquid with a strong, sweet odor. 1-(4-CHLOROPHENOXY)-2-PROPANONE is commonly used in the synthesis of various pharmaceuticals, such as the sedative and anesthetic methaqualone. Additionally, it is utilized in the production of pesticides and other organic compounds. This chemical is considered to be a hazardous substance and should be handled with caution, as it can cause irritation to the eyes, skin, and respiratory system. Furthermore, it is important to take measures to prevent its release into the environment, as it may have harmful effects on aquatic life.

InChI:InChI=1/C9H9ClO2/c1-7(11)6-12-9-4-2-8(10)3-5-9/h2-5H,6H2,1H3

Upstream product

• 106-48-9 4-chloro-phenol 
• 78-95-5 chloroacetone 
• 598-31-2 1-bromoacetone 
• 13997-70-1 1-allyloxy-4-chlorobenzene 
• 2684-62-0 diazoacetone 
• 584-08-7 potassium carbonate 
• 75-56-9 methyloxirane 

Downstream Products

• 21141-14-0 [β-(4-chloro-phenoxy)-isopropyl]-methyl-amine 
• 134671-47-9 sulfate de la N-<(1-<4'-chlorophenoxymethyl>ethylidene)amino>-N'-hydroxyguanidine 
• 104864-65-5 4-chlorophenoxyacetone oxime 
• 218770-30-0 1-Chloro-4-(2-cyclopropylidene-propoxy)-benzene 
• 23471-45-6 1-methyl-2-p-chlorophenoxyethylamine 
• 23471-46-7 1-(4-chlorophenoxy)-2-propanamine hydrochloride 
• 247199-97-9 2-amino-2-methyl-3-(4-chlorophenoxy)propanenitrile 

Relevant articles and documents

Linear Free Energy Correlation Analysis on the Electronic Effects of Rh(II) Carbene O-H Insertion

The relative rate constants for the Rh(II)-catalyzed insertion of diazoacetone into the O-H bond have been measured through intermolecular competitions. The kinetic data were subjected to Hammett correlation analysis, and mechanistic implication of the results with respect to a stepwise vs a concerted O-H insertion pathway is discussed.

Selective aerobic oxidation of allyl phenyl ether to methyl ketone by palladium–polyoxometalate hybrid catalysts

In this study, we report that selective aerobic oxidation of allyl phenyl ethers is attained by a Pd catalyst/polyoxometalate hybrid system to yield corresponding methyl ketones in water-enriched acetonitrile. The Pd(OAc)2/H5PV2Mo10O40 system exhibits higher conversions and yields of corresponding methyl ketone by Wacker-type oxidation of allyl phenyl ether as compared with the conventional PdCl2/CuCl2 system. The higher yields are attributed to the efficient re-oxidation of Pd0 to Pd2+ by H5PV2Mo10O40 using O2 as an oxidant as evidenced by electrochemical measurements. A reduced species of H5PV2Mo10O40 by Pd0 during the catalytic oxidation is revealed by UV–vis spectral measurements. The use of PdCl2 in place of Pd(OAc)2 in combination with [PV2Mo10O40]5? bearing tetraalkylammonium counter cations has also exhibited comparable conversions and product yields in the Wacker-type oxidation of allyl phenyl ethers. Para-substituted allyl phenyl ether derivatives are successfully oxidized in the Pd catalyst/polyoxometalate system to yield corresponding methyl ketones. The initial rate of products of para-substituted methyl ketones depended on the electronic effect of the substituents in which allyl phenyl ethers with electron-donating groups have accelerated the initial rate in the Pd catalyst/polyoxometalate system.

A (different) bright ammonia amide carbamate derivative and application thereof (by machine translation)

The invention belongs to the field of plant, relates to a general formula (I) is shown in a (different) bright ammonia amide carbamate derivatives and their pharmaceutically acceptable salt, wherein substituent R has the definition given in the specification, the invention also relates to the general formula (I) preparation of compounds of the, specifically for the preparation of the intermediate of its development and application of plant disease control. (by machine translation)