18942-46-6 Usage
Description
BOC-CYS(4-MEOBZL)-OH, also known as Boc-Cys(Mob)-OH, is a Cystine derivative that plays a crucial role in various chemical synthesis and peptide chemistry. It is characterized by its unique chemical structure, which allows it to be a versatile building block for the development of complex molecules and compounds.
Uses
Used in Chemical Synthesis:
BOC-CYS(4-MEOBZL)-OH is used as a key intermediate in the chemical synthesis of various compounds. Its unique structure enables the formation of new bonds and the creation of diverse molecular architectures, making it an essential component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Peptide Chemistry:
In the field of peptide chemistry, BOC-CYS(4-MEOBZL)-OH is employed as a building block for the synthesis of peptides and proteins. Its incorporation into peptide sequences allows for the creation of novel bioactive molecules with potential applications in drug discovery, diagnostics, and therapeutics.
Used in Pharmaceutical Industry:
BOC-CYS(4-MEOBZL)-OH is used as a crucial component in the development of new drugs. Its unique properties enable the design and synthesis of innovative pharmaceutical compounds with improved efficacy, selectivity, and safety profiles.
Used in Agrochemical Industry:
In the agrochemical industry, BOC-CYS(4-MEOBZL)-OH is utilized in the synthesis of novel bioactive molecules with potential applications in crop protection, pest control, and other agricultural practices. Its incorporation into these molecules can lead to the development of more effective and environmentally friendly agrochemicals.
Used in Research and Development:
BOC-CYS(4-MEOBZL)-OH is also used in research and development laboratories for the exploration of new chemical reactions, the synthesis of novel compounds, and the investigation of their biological activities. Its unique properties make it an invaluable tool for scientists and researchers working in various fields, including chemistry, biology, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 18942-46-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,4 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 18942-46:
(7*1)+(6*8)+(5*9)+(4*4)+(3*2)+(2*4)+(1*6)=136
136 % 10 = 6
So 18942-46-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H23NO5S/c1-16(2,3)22-15(20)17-13(14(18)19)10-23-9-11-5-7-12(21-4)8-6-11/h5-8,13H,9-10H2,1-4H3,(H,17,20)(H,18,19)/t13-/m1/s1
18942-46-6Relevant articles and documents
Two new procedures for the introduction of benzyl-type protecting groups for thiols
Richter, Lutz S.,Marsters Jr., James C.,Gadek, Thomas R.
, p. 1631 - 1634 (1994)
Two new methods for the benzylation of thiols are described: a) direct-S- alkylation with para-substituted benzylic cations; and b) reductive S- alkylations of 2-aminothiols. Both methods provide efficient routes for the introduction of benzyl-type protecting groups in high yields.
A comprehensive one-pot synthesis of protected cysteine and selenocysteine SPPS derivatives
Flemer, Stevenson
, p. 1257 - 1264 (2015/04/14)
A proof-of-principle methodology is presented in which all commercially-available cysteine (Cys) and selenocysteine (Sec) solid phase peptide synthesis (SPPS) derivatives are synthesized in high yield from easily prepared protected dichalcogenide precursors. A Zn-mediated biphasic reduction process applied to a series of four bis-Nα-protected dichalcogenide compounds allows facile conversion to their corresponding thiol and selenol intermediates followed by insitu S- or Se-alkylation with various electrophiles to directly access twenty one known Cys and Sec SPPS derivatives. Most of these derivatives were able to be precipitated in crude form out of petroleum ether in sufficient purity for direct use as peptide building blocks. Subsequent incorporation of these derivatives into peptide models nicely illustrates their viability and applicability toward SPPS.
INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS
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Page/Page column 20, (2010/08/22)
The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.
INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT
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Page/Page column 22, (2010/12/18)
The present invention relates to a composition for preserving cells, tissues and organs, comprising as an active ingredient indole and indazole compounds of formula (1), or a pharmaceutically acceptable salt or isomer thereof, which are effective for preventing injury of organs, isolated cell systems or tissues caused by cold storage, transplant operation or post-transplantation reperfusion; a preservation method; and a preparation method of the composition.
