66960-27-8Relevant articles and documents
A tetrameric enkephalin analog for the putative multivalent interaction with opioid receptors
Kondo,Kitajima,Yasunaga,Kodama,Costa,Shimohigashi
, p. 3161 - 3167 (1995)
Based on increased affinity and selectivity of dimeric enkephalin analogs for opioid receptors, divalent interactions have been demonstrated between opioid peptides and receptors. To explore the receptor multivalency suggested by fluorescent microscopic s
Exclusive affinity-labeling of μ opioid receptors by morphiceptin analogs containing S-(3-nitro-2-pyridylthio)cysteine
Motoyama, Shihoko,Takada, Kiyoshi,Yasunaga, Teruo,Fujita, Tsugumi,Shimohigashi, Yasuyuki
, p. 3607 - 3612 (2007/10/03)
The S-(3-nitro-2-pyridylthio) (Npys) group only reacts with a free mercapto group to form a disulfide bond. A series of morphiceptin analogs containing SNpys-cysteine were designed and synthesized for specific affinity-labeling of μ opioid receptors. Affi