19061-34-8Relevant articles and documents
Preparation of polyfunctional arynes via 2-magnesiated diaryl sulfonates
Sapountzis, Ioannis,Lin, Wenwei,Fischer, Markus,Knochel, Paul
, p. 4364 - 4366 (2007/10/03)
The synthetic potential of arynes can be exploited through a new method for their generation from functionalized aryl magnesium reagents and controlled reaction. Arynes with functional groups such as ester, nitrile, ketone, or nitro groups, or with a quinolyl skeleton, can be formed from polyfunctionalized 2-iodo aryl 4-chlorobenezenesulfonates and trapped in 68-93% yield with furan (see scheme).