19298-14-7

Basic information

• Product Name: 2-(2-Hydroxyethyl)-p-phenylenediamine
• Synonyms: 2-(2-Hydroxyethyl)-p-phenylenediamine;4-(2-HydroxyethylaMino)aniline
• CAS NO: 19298-14-7
• Molecular Formula: C₈H₁₂N₂O
• Molecular Weight: 152.1937
• Mol File: 19298-14-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 360.771 °C at 760 mmHg
• Flash Point: 171.988 °C
• Appearance: /
• Density: 1.216 g/cm³
• CAS DataBase Reference: 2-(2-Hydroxyethyl)-p-phenylenediamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Hydroxyethyl)-p-phenylenediamine(19298-14-7)
• EPA Substance Registry System: 2-(2-Hydroxyethyl)-p-phenylenediamine(19298-14-7)

Safety Data

• Hazardous Substances Data: 19298-14-7(Hazardous Substances Data)

Usage

General Description

2-(2-Hydroxyethyl)-p-phenylenediamine, also known as Toluene-2,5-diamine, is a chemical compound commonly used in hair dyes and textile dyes. It is an aromatic amine with a hydroxyethyl substituent, and it acts as a colorant and an antioxidant in various cosmetic products. However, it has been linked to skin irritation and allergic reactions in some individuals, and there is concern about its potential carcinogenic properties. Due to these health risks, its use in cosmetic products is regulated in some countries, and it is important for individuals to be aware of its presence in products and to use them with caution.

Upstream product

• 1965-54-4 N-(2-hydroxyethyl)-4-nitroaniline 
• 96-49-1 [1,3]-dioxolan-2-one 
• 106-50-3 1,4-phenylenediamine 
• 141-43-5 ethanolamine 
• 350-46-9 4-Fluoronitrobenzene 
• 890051-96-4 N-(2-{[tert-butyl(dimethyl)silyl]oxy}ethyl)phenylene-1,4-diamine 

Downstream Products

• 959153-96-9 5-chloro-N-(2-{4-[(2-hydroxyethyl)amino]phenyl}-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)thiophene-2-carboxamide 
• 1414781-20-6 2-(4-(4-(cyclopentylamino)-5-nitropyrimidin-2-ylamino)phenylamino)ethanol 
• 1807455-76-0 C₂₅H₂₄Cl₂N₄O₆S₂ 
• 1151893-81-0 2-{2-[1-(5-chlorothiophen-2-yl)-N-{4-[(5S)-5-{[(5-chlorothiophen-2-yl)formamido]methyl}-2-oxo-1,3-oxazolidin-3-yl]phenyl}formamido]ethoxy}acetic acid 

Relevant articles and documents

VEGFR TYROSINE KINASE INHIBITORS

Novel compounds, their prodrugs, and the pharmaceutically acceptable salts as pharmaceutical compositions containing such compounds useful in treating certain diseases modulated by the inhibition of vascular endothelial growth factors (VEGFs) receptor tyrosine kinases are provided. In particular, compounds and compositions and the methods for the prophylaxis, management and treatment of cancers through the inhibition of VEGF receptor tyrosine kinases are provided.

Isoindolin-1-One-, Isoindolin-3-One- and Isoindolin-1,3-Dione-Derivatives and Use Thereof

The invention relates to novel isoindolin-1-one, isoindolin-3-one and isoindoline-1,3-dione derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.

4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS

The present invention provides 4-hydroxyquinoline-3-carboxamide and hydrazide compounds of formula I These compounds are useful to treat or prevent the herpesviral infections, particularly, human cytomegaloviral infection.