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194222-05-4

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194222-05-4 Usage

General Description

3-exo-Hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester is a chemical compound with the molecular formula C12H21NO3. It is a tert-butyl ester derivative of 3-exo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylic acid and is commonly used as a building block in the synthesis of various pharmaceutical compounds. 3-exo-Hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester is a bicyclic structure containing a tertiary amine and a carboxylic acid functional group, making it useful in medicinal chemistry research and drug development. Its unique structure and functional groups make it a valuable intermediate for the production of potential pharmaceutical substances.

Check Digit Verification of cas no

The CAS Registry Mumber 194222-05-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,2,2 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 194222-05:
(8*1)+(7*9)+(6*4)+(5*2)+(4*2)+(3*2)+(2*0)+(1*5)=124
124 % 10 = 4
So 194222-05-4 is a valid CAS Registry Number.

194222-05-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl (1S,5R)-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:194222-05-4 SDS

194222-05-4Relevant articles and documents

Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation

Avenoza, Alberto,Bernardes, Gon?alo J. L.,Busto, Jesús H.,Corzana, Francisco,Ferhati, Xhenti,García-Sanmartín, Josune,Garrido, Pablo,Guerreiro, Ana,Jiménez-Moreno, Ester,Martínez, Alfredo,Peregrina, Jesús M.,Salas-Cubero, Marina

supporting information, p. 8580 - 8584 (2021/11/17)

A self-immolative bioorthogonal conditionally cleavable linker based on Grob fragmentation is described. It is derived from 1,3-aminocyclohexanols and allows the release of sulfonate-containing compounds in aqueous media. Modulation of the amine pKa promo

MODULATION OF N-ACYLETHANOLAMINE-HYDROLYSING ACID AMIDASE (NAAA) FOR DISEASE TREATMENT

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Paragraph 0025-0029, (2019/05/18)

Pharmaceutical compositions make up a compound acting as inhibitor of N-acylethanolamine-hydrolysing acid amidase (NAAA), may be used for the therapeutical treatment and prevention of pain and inflammatory disorders and other disorders which benefit from

CYCLOHEXANE ANALOGUES AS GPR119 AGONISTS

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, (2012/03/12)

This invention relates to a series of substituted cyclohexane containing analogues which are agonists of GPR119 intended to treat metabolic diseases mediated by GPR119 including Type I & II diabetes mellitus. Diabetes mellitus is an ever-increasing threat to human health causing various complications (blindness, kidney failure, neuropathy, heart attack, stroke, etc.). Recently it was found that activation of GPR119 which is highly expressed in pancreatic beta cells causes glucose dependent insulin secretion and GLP-1 release. Many pharmaceuticals are currently developing GPR119 agonists and herein we disclose alternative GPR119 agonists. Our invention describes GPR119 agonists having structural Formula (I), pharmaceutically acceptable salt or solvate of Formula (I), isomer or prodrug of Formula (I), and combination therapy of Formula (I) with other anti-diabetic drugs like DPP-IV inhibitors and/or insulin sensitizers.

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