198967-23-6

Basic information

• Product Name: 4-CHLORO-2-FLUORO-N-METHOXY-N-METHYLBENZAMIDE
• Synonyms: 4-CHLORO-2-FLUORO-N-METHOXY-N-METHYLBENZAMIDE;4-chloro-2-fluoro-N-methyl-N-(methyloxy)benzamide
• CAS NO: 198967-23-6
• Molecular Formula: C₉H₉ClFNO₂
• Molecular Weight: 217.62
• Mol File: 198967-23-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 338.993 °C at 760 mmHg
• Flash Point: 158.818 °C
• Appearance: /
• Density: 1.301 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-CHLORO-2-FLUORO-N-METHOXY-N-METHYLBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2-FLUORO-N-METHOXY-N-METHYLBENZAMIDE(198967-23-6)
• EPA Substance Registry System: 4-CHLORO-2-FLUORO-N-METHOXY-N-METHYLBENZAMIDE(198967-23-6)

Safety Data

• Hazardous Substances Data: 198967-23-6(Hazardous Substances Data)

Usage

General Description

4-CHLORO-2-FLUORO-N-METHOXY-N-METHYLBENZAMIDE is a chemical compound with the molecular formula C9H10ClFNO2. It is a derivative of benzamide and contains a chlorine and fluorine atom, as well as a methoxy and methyl group. 4-CHLORO-2-FLUORO-N-METHOXY-N-METHYLBENZAMIDE is commonly used in organic synthesis and pharmaceutical research for the development of new drugs. Its specific properties and potential applications in various industries make it a valuable component in the field of chemistry and pharmacology.

InChI:InChI=1/C9H9ClFNO2/c1-12(14-2)9(13)7-4-3-6(10)5-8(7)11/h3-5H,1-2H3

Upstream product

• 1117-97-1 N,0-dimethylhydroxylamine 
• 446-30-0 4-chloro-2-fluorobenzoic acid 
• 394-39-8 4-chloro-2-fluorobenzoyl chloride 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 1002095-66-0 1-(4-chloro-2-fluorophenyl)-3-methyl-1-butanone 
• 175711-83-8 4’-chloro-2’-fluoroacetophenone 
• 1158955-25-9 C₁₂H₅ClF₃NO 
• 1261595-05-4 (4-chloro-2-fluorophenyl)(pyridin-3-yl)-methanone 
• 1374584-30-1 bis(4-chloro-2-fluorophenyl)pyridin-3-yl methanol 
• 1374584-32-3 (4-chloro-2-fluorophenyl)(thiophen-2-yl)pyridin-3-yl methanol 
• 1374584-43-6 (4-chloro-2-fluorophenyl)[2-(propan-2-yloxy)pyrimidin-5-yl]-pyridin-3-yl methanol 

Relevant articles and documents

Analogues of fenarimol are potent inhibitors of trypanosoma cruzi and are efficacious in a murine model of chagas disease

We report the discovery of nontoxic fungicide fenarimol (1) as an inhibitor of Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, and the results of structure-activity investigations leading to potent analogues with low nM IC50s in a T. cruzi whole cell in vitro assay. Lead compounds suppressed blood parasitemia to virtually undetectable levels after once daily oral dosing in mouse models of T. cruzi infection. Compounds are chemically tractable, allowing rapid optimization of target biological activity and drug characteristics. Chemical and biological studies undertaken in the development of the fenarimol series toward the goal of delivering a new drug candidate for Chagas disease are reported.

Benzylamine derivatives which are useful in treating psychiatric disorders

The present invention relates to certain novel benzylamine derivatives, to processes for their preparation, to pharmaceutical formulations containing them and to their use in medical therapy, particularly in the treatment of depression.